The effects of common peroneal nerve electrical stimulation on lower extremity deep venous hemodynamics: A randomized, crossover and controlled study

• Published in: Medicine (Baltimore) 2024-12, Vol.103 (50), p.e40847
• Main Authors: Zou, Zhao-Jun, Song, Hai-Xin, Wang, Ting, Ma, Hai-Yun, Cao, Li-Ping, Wu, Tao
• Format: Article
• Language: English
• Subjects: Adult; Blood Flow Velocity - physiology; Clinical Trial/Experimental Study; Cross-Over Studies; Electric Stimulation Therapy - methods; Female; Femoral Artery - physiology; Femoral Vein - physiology; Healthy Volunteers; Hemodynamics - physiology; Humans; Intermittent Pneumatic Compression Devices; Lower Extremity - blood supply; Male; Peroneal Nerve - physiology; Young Adult
• ISSN: 0025-7974; 1536-5964; 1536-5964
• DOI: 10.1097/MD.0000000000040847

Intermittent pneumatic compression (IPC) and neuromuscular electrical stimulation can improve deep vein hemodynamics in the lower limbs. We developed a new, small and convenient, and easy to wear common peroneal nerve electrical stimulator (CPNES) and to investigate the effectiveness and safety of CPNES intervention on deep venous hemodynamics. Thirty healthy volunteers were recruited and randomly divided into group A and B. In group A, the hemodynamics of the left superficial femoral artery and the superficial femoral vein were measured after IPC compression, and then the CPNES was activated and the hemodynamics was measured again. In group B, the order of intervention was reversed. In group A, the peak velocity, time average blood flow velocity (TAMV), and flow velocity of femoral vein after IPC and CPNES intervention were higher than these of the baseline (P  .05, respectively). In group B, these blood flow parameters of femoral vein after IPC and CPNES intervention were higher than these of the baseline (P  .05, respectively) were noted between IPC and CPNES intervention as well. No differential change of these flow velocity of femoral artery after IPC and CPNES intervention in group A or group B. The hemodynamics of superficial femoral arteries and veins after intervention in group A and B were similar (P > .05, respectively). The effectiveness of CPNES intervention on the hemodynamics of the lower extremity is similar with that of IPC, increasing blood flow and may prevent venous thrombosis without adverse reaction.