Impact of Sex on Outcomes With Femoral Artery Closure Devices Versus Manual Compression in Patients Undergoing Percutaneous Coronary Intervention

ABSTRACT Background and Aims Femoral artery access is widely used despite recent increase in radial access for percutaneous coronary interventions (PCI). Femoral artery closure devices are used to shorten vascular closure time and reduce bleeding. We sought to examine sex‐based outcomes of femoral a...

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Bibliographic Details
Published in:Health science reports 2024-12, Vol.7 (12), p.e70256-n/a
Main Authors: Anderson, Wesley L., Torabi, Asad J., O'leary, Brian A., Breall, Jeffrey A., Sinha, Anjan K., Jaradat, Ziad A., Morris, Michelle C., Frick, Kyle A., Romeh, Ibrahim A., Iqtidar, Ali F., Lohe, Elisabeth, Kreutz, Rolf P.
Format: Article
Language:English
Subjects:
Angioplasty
bleeding
Blood transfusions
Body mass index
Cardiac arrest
cardiac catheterization
Cardiology
Clinical outcomes
Demographics
Diabetes
Endocrinology and Metabolic Disorders
Epidemiology
Females
Gastroenterology/Hepatology
General Medicine
Genetics and Genomics
Glycoproteins
Heart attacks
Hematoma
Hemoglobin
Hyperlipidemia
Hypertension
Immunology
Infectious Diseases
Kidney diseases
Lung diseases
Mortality
Original Research
Patients
percutaneous coronary intervention, sex, women, vascular closure devices
Radiology & Imaging
Statistical analysis
Surgery
Ultrasonic imaging
Variables
Veins & arteries
Venous access
Womens health
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Summary:ABSTRACT Background and Aims Femoral artery access is widely used despite recent increase in radial access for percutaneous coronary interventions (PCI). Femoral artery closure devices are used to shorten vascular closure time and reduce bleeding. We sought to examine sex‐based outcomes of femoral artery vascular closure devices (VCD) in patients undergoing PCI. Methods We identified patients who had undergone PCI (n = 11,415) in the Indiana University Health Multicenter Cardiac Cath registry using femoral artery access. Clinical outcomes were compared between VCD and manual compression and analyzed according to sex. Patients with cardiogenic shock and left ventricular support devices were excluded. Results The use of any vascular closure device as compared to femoral artery manual compression was associated with a reduction in 72‐h bleeding events (adjusted odds ratio [OR]: 0.64; 95% confidence interval [CI]: 0.46–0.87). With manual compression, women had higher rates of 72‐h bleeding as compared to men (4.5% vs. 1.6%, p 
ISSN:2398-8835
2398-8835
DOI:10.1002/hsr2.70256