Relationship between exosomes and cancer: formation, diagnosis, and treatment

Exosomes are a member of extracellular vesicles. However, their biological characteristics differ from those of other vesicles, and recently, their powerful functions as information molecules, biomarkers, and carriers have been demonstrated. Malignancies are the leading cause of high morbidity and m...

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Bibliographic Details
Published in:International journal of biological sciences 2025, Vol.21 (1), p.40-62
Main Authors: Huang, Chen, Li, Jiajin, Xie, Zichuan, Hu, Xiangjun, Huang, Yan
Format: Article
Language:English
Subjects:
Animals
Biomarkers, Tumor - metabolism
Exosomes - metabolism
Humans
Neoplasms - diagnosis
Neoplasms - metabolism
Neoplasms - therapy
Review
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Summary:Exosomes are a member of extracellular vesicles. However, their biological characteristics differ from those of other vesicles, and recently, their powerful functions as information molecules, biomarkers, and carriers have been demonstrated. Malignancies are the leading cause of high morbidity and mortality worldwide. The cure rate of malignancies can be improved by improving early screening rates and therapy. Moreover, a close correlation between exosomes and malignancies has been observed. An in-depth study of exosomes can provide new methods for diagnosing and treating tumors. Therefore, this study aimed to review, sort, and summarize such achievements, and present ideas and opinions on the application of exosomes in tumor treatment.
ISSN:1449-2288
1449-2288
DOI:10.7150/ijbs.95763