Unveiling the intricacies: Insight into gastroesophageal reflux disease

Gastroesophageal reflux disease (GERD) poses a substantial global health challenge, with prevalence rates exhibiting geographical variation. Despite its widespread recognition, the exact prevalence and associated risk factors remain elusive. This article comprehensively analyzed the global burden of...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2025-01, Vol.31 (1), p.98479
Main Authors: Wickramasinghe, Nilanka, Devanarayana, Niranga Manjuri
Format: Article
Language:English
Subjects:
Gastroesophageal Reflux - diagnosis
Gastroesophageal Reflux - epidemiology
Gastroesophageal Reflux - physiopathology
Gastroesophageal Reflux - therapy
Global Health - statistics & numerical data
Humans
Prevalence
Review
Risk Factors
Treatment Failure
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Description
Summary:Gastroesophageal reflux disease (GERD) poses a substantial global health challenge, with prevalence rates exhibiting geographical variation. Despite its widespread recognition, the exact prevalence and associated risk factors remain elusive. This article comprehensively analyzed the global burden of GERD, shedding light on its risk factors, underlying pathophysiological mechanisms, current diagnostic modalities, evolving management strategies tailored to diverse patient profiles, and complex determinants contributing to treatment failures. A deeper comprehension of GERD is achieved by dissecting these intricate facets, paving the way for enhanced clinical management and improved patient outcomes.
ISSN:1007-9327
2219-2840
2219-2840
DOI:10.3748/wjg.v31.i1.98479