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Mortality in patients with giant cell arteritis in Spain: results from the ARTESER registry

To compare mortality rates between GCA patients and the general population in Spain, and to identify associated factors influencing mortality. ARTESER, a multicenter registry by the Spanish Society of Rheumatology, includes GCA patients from June 2013 to March 2019. Demographic, clinical, imaging, h...

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Published in:Arthritis research & therapy 2025-01, Vol.27 (1), p.4-10, Article 4
Main Authors: Molina-Collada, Juan, Domínguez-Álvaro, Marta, Melero-González, Rafael B, de Miguel, Eugenio, Silva-Díaz, Maite, Valero Jaimes, Jesús Alejandro, González, Ismael, Sánchez Martín, Julio, Narváez, Javier, Calvet, Joan, Casafont-Solé, Ivette, Román Ivorra, Jose A, Labrada Arrabal, Selene, Vasques Rocha, Margarida, Iñiguez, Carlota L, Bustabad Reyes, María Sagrario, Campos Fernández, Cristina, Alcalde Villar, María, Mas, Antonio Juan, Blanco, Ricardo
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Language:English
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Summary:To compare mortality rates between GCA patients and the general population in Spain, and to identify associated factors influencing mortality. ARTESER, a multicenter registry by the Spanish Society of Rheumatology, includes GCA patients from June 2013 to March 2019. Demographic, clinical, imaging, histological and mortality data were collected retrospectively. Only patients with at least one year of follow-up were included for analysis. The mortality rates were expressed as the number of deaths per 1000 person-years, with 95% confidence interval (CI) by sex and age group. Kaplan-Meier method was performed for survival analysis. The factors influencing mortality were analyzed using Cox regression model. A total of 1200 patients with GCA were analyzed, with a mean (SD) follow-up of 2.18 (1.53) years. The overall five-year cumulative mortality rate (95%CI) was 37.86 (31.75-43.96) per 1000 patients/year. The cumulative mortality rate was significantly higher in males than females (59.04vs29.06; p
ISSN:1478-6362
1478-6354
1478-6362
DOI:10.1186/s13075-024-03468-6