Tyrosine aminotransferase activity in the rabbit placenta. Evidence for decreased inducibility by insulin and cortisol as a function of gestational age

Tyrosine aminotransferase is present at low activity in the rabbit placenta. The activity can be enhanced by injecting the pregnant mother with insulin or cortisol. This response decreases over the last half of gestation (14-28 days gestational age).

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Bibliographic Details
Published in:Biochemical journal 1976-01, Vol.154 (1), p.245-247
Main Authors: Wade, R S, Gusseck, D J
Format: Article
Language:English
Subjects:
Animals
Enzyme Induction - drug effects
Female
Gestational Age
Hydrocortisone - pharmacology
Insulin - pharmacology
Liver - enzymology
Placenta - drug effects
Placenta - enzymology
Pregnancy
Rabbits
Time Factors
Tyrosine Transaminase - metabolism
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Description
Summary:Tyrosine aminotransferase is present at low activity in the rabbit placenta. The activity can be enhanced by injecting the pregnant mother with insulin or cortisol. This response decreases over the last half of gestation (14-28 days gestational age).
ISSN:0264-6021
1470-8728
DOI:10.1042/bj1540245