A Case of Atraumatic Splenic Rupture Due to T-Cell/Histiocyte-Rich Large B-Cell Lymphoma and a Potential Role for Massive Transfusion Protocol

Splenic rupture leads to massive hemorrhage and requires immediate surgical intervention. Splenic rupture results from trauma or from underlying disease processes. Lymphoma is a rare cause of atraumatic splenic rupture (ASR) with high mortality rates. We present a case of ASR due to T-cell/histiocyt...

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Bibliographic Details
Published in:Case reports in surgery 2025-01, Vol.2025 (1), p.4069182
Main Authors: Bohjanen, Sara, Ratanawong, John P, Baumgartner, Mary, Chandler, Bree, Manivel, J Carlos, Rezcallah, Anthony T
Format: Article
Language:English
Subjects:
Abdomen
Aortic aneurysms
B cells
B-cell lymphoma
Blood platelets
Blood products
Case Report
Consent
Emergency medical care
Epstein-Barr virus
Etiology
Health aspects
Hemodynamics
Hemoglobin
Hemorrhage
Injuries
Laparotomy
Lymphatic system
Lymphocytes B
Lymphocytes T
Lymphoma
Lymphomas
Mortality
Patients
Rupture
Spleen
Splenectomy
Surgery
Transfusion
Trauma
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Summary:Splenic rupture leads to massive hemorrhage and requires immediate surgical intervention. Splenic rupture results from trauma or from underlying disease processes. Lymphoma is a rare cause of atraumatic splenic rupture (ASR) with high mortality rates. We present a case of ASR due to T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) requiring splenectomy and large-volume transfusion. This case report highlights the necessity of prompt surgical intervention and massive transfusion for hemodynamically unstable ASR. This report also discusses massive transfusion protocol (MTP) and its limited use in nontraumatic surgical patients.
ISSN:2090-6900
2090-6919
DOI:10.1155/cris/4069182