Micronutrient deficiencies and new-onset atrial fibrillation in a community-based cohort: data from PREVEND

Aim Malnutrition has been linked to cardiovascular diseases. Both selenium and iron deficiency have been associated with worse prognosis in patients with heart failure (HF). Yet, little is known about the role of micronutrients in the development of atrial fibrillation (AFib). In this study, we aime...

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Bibliographic Details
Published in:Clinical research in cardiology 2025, Vol.114 (1), p.41-52
Main Authors: Al-Mubarak, Ali A., Grote Beverborg, Niels, Zwartkruis, Victor, van Deutekom, Colinda, de Borst, Martin H., Gansevoort, Ron T., Bakker, Stephan J. L., Touw, Daan J., de Boer, Rudolf A., van der Meer, Peter, Rienstra, Michiel, Bomer, Nils
Format: Article
Language:English
Subjects:
Aged
Atrial Fibrillation - blood
Atrial Fibrillation - diagnosis
Atrial Fibrillation - epidemiology
Atrial Fibrillation - etiology
Cardiac arrhythmia
Cardiology
Cardiomyocytes
Cardiovascular diseases
Congestive heart failure
Female
Ferritin
Fibrillation
Follow-Up Studies
Heart diseases
Humans
Incidence
Iron
Iron - blood
Iron Deficiencies
Iron deficiency
Magnesium
Magnesium - blood
Magnesium Deficiency - blood
Magnesium Deficiency - complications
Magnesium Deficiency - epidemiology
Male
Malnutrition
Medicine
Medicine & Public Health
Micronutrients
Micronutrients - blood
Micronutrients - deficiency
Middle Aged
Nutrient deficiency
Original Paper
Population studies
Prognosis
Prospective Studies
Risk Factors
Selenium
Selenium - blood
Selenium - deficiency
Smoking
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Summary:Aim Malnutrition has been linked to cardiovascular diseases. Both selenium and iron deficiency have been associated with worse prognosis in patients with heart failure (HF). Yet, little is known about the role of micronutrients in the development of atrial fibrillation (AFib). In this study, we aimed to elucidate the association of micronutrient deficiencies with new-onset AFib. Methods Selenium, magnesium, and iron parameters were measured in a well-characterized prospective cohort study ( N  = 5452). Selenium deficiency was defined as serum selenium 
ISSN:1861-0684
1861-0692
DOI:10.1007/s00392-023-02276-3