Relative changes in the function of muscle ribosomes and mitochondria during the early phase of steroid-induced catabolism

1. Five glucocorticoids, when administered daily to rats for 5-7 days at a dosage of 5mg/kg, were in the following order of effectiveness with respect to their ability to decrease the weight gain of whole animals and the vastus lateralis, vastus medialis and gluteus medius muscles: corticosterone

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Bibliographic Details
Published in:Biochemical journal 1972-05, Vol.127 (5), p.881-892
Main Authors: Bullock, G R, Carter, E E, Elliott, P, Peters, R F, Simpson, P, White, A M
Format: Article
Language:English
Subjects:
Amino Acids - metabolism
Animals
Betamethasone - pharmacology
Body Weight - drug effects
Carbon Isotopes
Corticosterone - pharmacology
Dexamethasone - pharmacology
Dose-Response Relationship, Drug
Glucocorticoids - pharmacology
Leucine - metabolism
Male
Mitochondria, Muscle - drug effects
Muscles - cytology
Muscles - drug effects
Muscles - metabolism
Oxidation-Reduction
Prednisolone - pharmacology
Rats
Ribosomes - drug effects
Triamcinolone - pharmacology
Triamcinolone Acetonide - pharmacology
Tritium
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Description
Summary:1. Five glucocorticoids, when administered daily to rats for 5-7 days at a dosage of 5mg/kg, were in the following order of effectiveness with respect to their ability to decrease the weight gain of whole animals and the vastus lateralis, vastus medialis and gluteus medius muscles: corticosterone
ISSN:0264-6021
0306-3283
1470-8728
DOI:10.1042/bj1270881