The Hox-2 Homeo Box Gene Complex on Mouse Chromosome 11 Is Closely Linked to Re

Restriction fragment length polymorphisms have been identified between inbred strains of mice for the homeo box gene complex Hox-2. These genetic markers were used to follow the segregation of different Hox-2 alleles among recombinant inbred strains of mice and among the progeny of a three point gen...

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Bibliographic Details
Published in:Genetics (Austin) 1988-02, Vol.118 (2), p.319-327
Main Authors: Hart, C. P, Dalton, D. K, Nichols, L, Hunihan, L, Roderick, T. H, Langley, S. H, Taylor, B. A, Ruddle, F. H
Format: Article
Language:English
Subjects:
Alleles
Animals
Biological and medical sciences
Chromosome Mapping
Classical genetics, quantitative genetics, hybrids
Crosses, Genetic
DNA Restriction Enzymes
Female
Fundamental and applied biological sciences. Psychology
Genes, Homeobox
Genetic Linkage
Genetics of eukaryotes. Biological and molecular evolution
Investigations
Male
Mice
Mice, Inbred Strains - genetics
Polymorphism, Genetic
Recombination, Genetic
Vertebrata
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Summary:Restriction fragment length polymorphisms have been identified between inbred strains of mice for the homeo box gene complex Hox-2. These genetic markers were used to follow the segregation of different Hox-2 alleles among recombinant inbred strains of mice and among the progeny of a three point genetic cross. The results place the Hoax-2 locus approximately 1 cM from the rex (Re) locus on mouse chromosome 11.
ISSN:0016-6731
1943-2631
1943-2631
DOI:10.1093/genetics/118.2.319