Developmental expression of the glucose dehydrogenase gene in Drosophila melanogaster

The Gld gene of Drosophila melanogaster is transiently expressed during every stage of development. The temporal pattern of Gld expression is highly correlated with that of ecdysteroids. Exogeneous treatment of third instar larvae with 20-hydroxyecdysone induces the accumulation of Gld mRNA in the h...

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Bibliographic Details
Published in:Genetics (Austin) 1990-04, Vol.124 (4), p.873-880
Main Authors: Cox-Foster, D.L. (Pennsylvania State University, University Park, PA), Schonbaum, C.P, Murtha, M.T, Cavener, D.R
Format: Article
Language:English
Subjects:
ACTIVIDAD ENZIMATICA
ACTIVITE ENZYMATIQUE
Animals
Biological and medical sciences
Blotting, Northern
Carbohydrate Dehydrogenases - genetics
CONTROL GENETICO
Diptera
DROSOPHILA
Drosophila melanogaster - enzymology
Drosophila melanogaster - genetics
Drosophila melanogaster - growth & development
Drosophilidae
Ecdysterone - biosynthesis
Ecdysterone - genetics
ENZYMIC ACTIVITY
Female
FENOTIPOS
Fundamental and applied biological sciences. Psychology
GENE
Gene expression
Gene Expression Regulation, Enzymologic
GENES
GENETIC CONTROL
GLUCOSA
GLUCOSE
Glucose Dehydrogenases - biosynthesis
Glucose Dehydrogenases - genetics
Investigations
LUTTE GENETIQUE
Male
Molecular and cellular biology
Molecular genetics
MUTANT
MUTANTES
MUTANTS
Nucleic Acid Hybridization
OXIDOREDUCTASES
OXIDORREDUCTASAS
OXYDOREDUCTASE
PHENOTYPE
PHENOTYPES
RNA, Messenger - analysis
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Description
Summary:The Gld gene of Drosophila melanogaster is transiently expressed during every stage of development. The temporal pattern of Gld expression is highly correlated with that of ecdysteroids. Exogeneous treatment of third instar larvae with 20-hydroxyecdysone induces the accumulation of Gld mRNA in the hypoderm and anterior spiracular gland cells. During metamorphosis Gld is expressed in a variety of tissues derived from the ectoderm. In the developing reproductive tract, Gld mRNA accumulates in the female spermathecae and oviduct and in the male ejaculatory duct and ejaculatory bulb. These four organs are derived from closely related cell lineages in the genital imaginal disc. Since the expression of Gld is not required for the development of these reproductive structures, this spatial pattern of expression is most likely a fortuitous consequence of a shared regulatory factor in this cell lineage. At the adult stage a high level of the Gld mRNA is only observed in the male ejaculatory duct.
ISSN:0016-6731
1943-2631
1943-2631
DOI:10.1093/genetics/124.4.873