Genetic analysis of suppressors of the veA1 mutation in Aspergillus nidulans

Light-dependent conidiation in the filamentous ascomycete, Aspergillus nidulans, is contingent on the allelic state of the velvet (veA) gene. Light dependence is abolished by a mutation in this gene (veA1), which allows conidiation to occur in the absence of light. We have isolated and characterized...

Full description

Saved in:
Bibliographic Details
Published in:Genetics (Austin) 1990-12, Vol.126 (4), p.869-874
Main Authors: Mooney, J.L. (University of Georgia, Athen, GA), Hassett, D.E, Yager, L.N
Format: Article
Language:English
Subjects:
Alleles
ASPERGILLUS NIDULANS
Aspergillus nidulans - genetics
Aspergillus nidulans - growth & development
Aspergillus nidulans - physiology
Biological and medical sciences
Classical genetics, quantitative genetics, hybrids
ESPORAS
ESPORULACION
Fundamental and applied biological sciences. Psychology
GENE
GENES
Genes, Dominant
Genes, Fungal
Genes, Suppressor
Genetic Complementation Test
GENETICA
Genetics of eukaryotes. Biological and molecular evolution
GENETIQUE
Investigations
Light
LUMIERE
LUZ
MUTACION
MUTATION
Phenotype
SPORE
Spores, Fungal
SPORULATION
Thallophyta, bryophyta
Vegetals
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Light-dependent conidiation in the filamentous ascomycete, Aspergillus nidulans, is contingent on the allelic state of the velvet (veA) gene. Light dependence is abolished by a mutation in this gene (veA1), which allows conidiation to occur in the absence of light. We have isolated and characterized six extragenic suppressors of veA1 that restore the light-dependent conidiation phenotype. Alleles of four genes, defined by complementation tests, were subjected to extensive genetic and phenotypic analysis. The results of light-dark shifting experiments and the phenotypes of double mutant combinations are consistent with the possibility that the expression of the light-dependent phenotype is regulated by specific interactions of the suppressor gene products with the velvet gene product and with each other
ISSN:0016-6731
1943-2631
1943-2631
DOI:10.1093/genetics/126.4.869