FLUCTUATIONS IN HUMAN SERUM LIPOPROTEINS DURING THE NORMAL MENSTRUAL CYCLE

1. Lipoproteins were measured in sera from 11 young women having a similar environment and diet. Sera were obtained at weekly intervals over a 12-week period. The values of the lipoproteins during periods in the normal ovulatory cycle were compared to assess their relation to reported hormone concen...

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Bibliographic Details
Published in:Biochemical journal 1965-07, Vol.96 (1), p.205-209
Main Authors: BARCLAY, M, BARCLAY, R K, SKIPSKI, V P, TEREBUS-KEKISH, O, MUELLER, C H, SHAH, E, ELKINS, W L
Format: Article
Language:English
Subjects:
Adult
Biomedical Research
Female
Humans
Lipids - blood
Lipoproteins
Lipoproteins, HDL
Menstrual Cycle
Menstruation
Old Medline
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Summary:1. Lipoproteins were measured in sera from 11 young women having a similar environment and diet. Sera were obtained at weekly intervals over a 12-week period. The values of the lipoproteins during periods in the normal ovulatory cycle were compared to assess their relation to reported hormone concentrations in blood. 2. Only the 4-0s(f) (HDL(2)) (d 1.125 sodium chloride) fraction changed significantly; it increased at ovulation in ten of the 11 subjects and fell as menstruation approached. 3. There was greater variability in most of the low-density rather than the high-density lipoproteins within individuals. The lipoprotein class most characteristic for an individual was the 4-0s(f) or HDL(2) fraction.
ISSN:0264-6021
1470-8728
DOI:10.1042/bj0960205