Colitis in calves: natural and experimental infection with a verotoxin-producing strain of Escherichia coli O111:NM

Verotoxin-producing Escherichia coli O111:NM were isolated from two five week old Holstein calves with dysentery. On necropsy both calves had pseudomembranous ileitis, mucohemorrhagic colitis and proctitis. Large numbers of E. coli O111:NM were isolated from the colon and lesions typical of attachin...

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Bibliographic Details
Published in:Canadian journal of veterinary research 1988-10, Vol.52 (4), p.484-487
Main Authors: Schoonderwoerd, M, Clarke, R C, van Dreumel, A A, Rawluk, S A
Format: Article
Language:English
Subjects:
Animals
Bacterial Toxins
Cattle
Cattle Diseases - microbiology
Cattle Diseases - pathology
Colitis - microbiology
Colitis - pathology
Colitis - veterinary
Escherichia coli - classification
Escherichia coli Infections - pathology
Escherichia coli Infections - veterinary
Male
Shiga Toxin 1
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Summary:Verotoxin-producing Escherichia coli O111:NM were isolated from two five week old Holstein calves with dysentery. On necropsy both calves had pseudomembranous ileitis, mucohemorrhagic colitis and proctitis. Large numbers of E. coli O111:NM were isolated from the colon and lesions typical of attaching-and-effacing E. coli were evident. The isolates from both calves had identical biochemical reactions and antimicrobial resistance patterns. Oral inoculation of a four day old colostrum deprived calf with 1 x 10(10) organisms of E. coli O111:NM produced a mild, focal colitis with typical attachment and effacement lesions. We conclude that the strain of E. coli O111:NM isolated from the clinical cases has the ability to produce colitis characterized by attachment and effacement of the colonic mucosa.
ISSN:0830-9000