Effects of hypothyroidism on the karyometric development of pyramidal neurons of the hippocampus (CA1), area 6 and area 17 in the male mouse

This study has examined the karyometric changes within pyramidal neurons of the hippocampus, motor area 6 and visual area 17 in a hypothyroid group of male mice treated with propylthiouracil, with or without interruption of treatment at the 35th postnatal day. Hypothyroidism resulted in decrease of...

Full description

Saved in:
Bibliographic Details
Published in:Journal of anatomy 1987-02, Vol.150, p.23-29
Main Authors: PEREZ-DELGADO, M. D. M, FERRES-TORRES, R, CASTANEYRA-PERDOMO, A, GONZALEZ-HERNANDEZ, T
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cell Nucleus - pathology
Cerebral Cortex - growth & development
Cerebral Cortex - pathology
Endocrinopathies
Hippocampus - growth & development
Hippocampus - pathology
Hypothyroidism - chemically induced
Hypothyroidism - pathology
Male
Medical sciences
Mice
Mice, Inbred Strains
Motor Cortex - pathology
Neurons - pathology
Neurons - ultrastructure
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Propylthiouracil
Thyroid. Thyroid axis (diseases)
Visual Cortex - pathology
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study has examined the karyometric changes within pyramidal neurons of the hippocampus, motor area 6 and visual area 17 in a hypothyroid group of male mice treated with propylthiouracil, with or without interruption of treatment at the 35th postnatal day. Hypothyroidism resulted in decrease of nuclear size in the three areas before puberty and even after puberty in the hippocampus. Where the treatment was continued throughout the experimental period there was a progressive increase of nuclear size in both visual and motor areas.
ISSN:0021-8782
1469-7580