Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases

• Published in: Antimicrobial Agents and Chemotherapy 2002-06, Vol.46 (6), p.1880-1886
• Main Authors: PAYNE, David J, HUESO-RODRIGUEZ, Juan Antonio, RITTENHOUSE, Stephen, TEW, David, DIEZ, Emilio, PEREZ, Paloma, DE LA FUENTE, Jesus, REES, Michael, RIVERA-SAGREDO, Alfonso, BODY, Helen, CONCHA, Néstor O, JANSON, Cheryl A, GILPIN, Martin, BATESON, John H, CHEEVER, Christy, NICONOVICH, Nancy L, PEARSON, Stewart
• Format: Article
• Language: English
• Subjects: Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacillus - drug effects; Bacillus cereus - drug effects; Bacillus cereus - enzymology; beta-Lactamase Inhibitors; beta-Lactamases - metabolism; Binding Sites; Biological and medical sciences; Biosynthesis; Chaetomium; Chaetomium - chemistry; Chaetomium - metabolism; Chemistry; Chemistry; Biosynthesis; Drug Synergism; Enzyme Inhibitors; Enzyme Inhibitors - pharmacology; Fermentation; Heterocyclic Compounds, 3-Ring; Heterocyclic Compounds, 3-Ring - pharmacology; Kinetics; Medical sciences; Meropenem; Microbial Sensitivity Tests; Models, Molecular; Pharmacology. Drug treatments; Thienamycins - pharmacology
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.46.6.1880-1886.2002

Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • [e-mail] Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC