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Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases
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Published in: | Antimicrobial Agents and Chemotherapy 2002-06, Vol.46 (6), p.1880-1886 |
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container_end_page | 1886 |
container_issue | 6 |
container_start_page | 1880 |
container_title | Antimicrobial Agents and Chemotherapy |
container_volume | 46 |
creator | PAYNE, David J HUESO-RODRIGUEZ, Juan Antonio RITTENHOUSE, Stephen TEW, David DIEZ, Emilio PEREZ, Paloma DE LA FUENTE, Jesus REES, Michael RIVERA-SAGREDO, Alfonso BODY, Helen CONCHA, Néstor O JANSON, Cheryl A GILPIN, Martin BATESON, John H CHEEVER, Christy NICONOVICH, Nancy L PEARSON, Stewart |
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doi_str_mv | 10.1128/AAC.46.6.1880-1886.2002 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.46.6.1880-1886.2002</identifier><identifier>PMID: 12019104</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Bacillus - drug effects ; Bacillus cereus - drug effects ; Bacillus cereus - enzymology ; beta-Lactamase Inhibitors ; beta-Lactamases - metabolism ; Binding Sites ; Biological and medical sciences ; Biosynthesis ; Chaetomium ; Chaetomium - chemistry ; Chaetomium - metabolism ; Chemistry ; Chemistry; Biosynthesis ; Drug Synergism ; Enzyme Inhibitors ; Enzyme Inhibitors - pharmacology ; Fermentation ; Heterocyclic Compounds, 3-Ring ; Heterocyclic Compounds, 3-Ring - pharmacology ; Kinetics ; Medical sciences ; Meropenem ; Microbial Sensitivity Tests ; Models, Molecular ; Pharmacology. Drug treatments ; Thienamycins - pharmacology</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2002-06, Vol.46 (6), p.1880-1886</ispartof><rights>2002 INIST-CNRS</rights><rights>Copyright © 2002 American Society for Microbiology</rights><rights>Copyright © 2002, American Society for Microbiology 2002</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a544t-98c245887f3e4085c9eba70444b75b17b382838ca2f38ebeb947dabe0248f34f3</citedby><cites>FETCH-LOGICAL-a544t-98c245887f3e4085c9eba70444b75b17b382838ca2f38ebeb947dabe0248f34f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.asm.org/doi/pdf/10.1128/AAC.46.6.1880-1886.2002$$EPDF$$P50$$Gasm2$$H</linktopdf><linktohtml>$$Uhttps://journals.asm.org/doi/full/10.1128/AAC.46.6.1880-1886.2002$$EHTML$$P50$$Gasm2$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,3188,3189,27924,27925,52751,52752,52753,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14187754$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12019104$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>PAYNE, David J</creatorcontrib><creatorcontrib>HUESO-RODRIGUEZ, Juan Antonio</creatorcontrib><creatorcontrib>RITTENHOUSE, Stephen</creatorcontrib><creatorcontrib>TEW, David</creatorcontrib><creatorcontrib>DIEZ, Emilio</creatorcontrib><creatorcontrib>PEREZ, Paloma</creatorcontrib><creatorcontrib>DE LA FUENTE, Jesus</creatorcontrib><creatorcontrib>REES, Michael</creatorcontrib><creatorcontrib>RIVERA-SAGREDO, Alfonso</creatorcontrib><creatorcontrib>BODY, Helen</creatorcontrib><creatorcontrib>CONCHA, Néstor O</creatorcontrib><creatorcontrib>JANSON, Cheryl A</creatorcontrib><creatorcontrib>GILPIN, Martin</creatorcontrib><creatorcontrib>BATESON, John H</creatorcontrib><creatorcontrib>CHEEVER, Christy</creatorcontrib><creatorcontrib>NICONOVICH, Nancy L</creatorcontrib><creatorcontrib>PEARSON, Stewart</creatorcontrib><title>Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Bacillus - drug effects</subject><subject>Bacillus cereus - drug effects</subject><subject>Bacillus cereus - enzymology</subject><subject>beta-Lactamase Inhibitors</subject><subject>beta-Lactamases - metabolism</subject><subject>Binding Sites</subject><subject>Biological and medical sciences</subject><subject>Biosynthesis</subject><subject>Chaetomium</subject><subject>Chaetomium - chemistry</subject><subject>Chaetomium - metabolism</subject><subject>Chemistry</subject><subject>Chemistry; Biosynthesis</subject><subject>Drug Synergism</subject><subject>Enzyme Inhibitors</subject><subject>Enzyme Inhibitors - pharmacology</subject><subject>Fermentation</subject><subject>Heterocyclic Compounds, 3-Ring</subject><subject>Heterocyclic Compounds, 3-Ring - pharmacology</subject><subject>Kinetics</subject><subject>Medical sciences</subject><subject>Meropenem</subject><subject>Microbial Sensitivity Tests</subject><subject>Models, Molecular</subject><subject>Pharmacology. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Bacillus - drug effects</topic><topic>Bacillus cereus - drug effects</topic><topic>Bacillus cereus - enzymology</topic><topic>beta-Lactamase Inhibitors</topic><topic>beta-Lactamases - metabolism</topic><topic>Binding Sites</topic><topic>Biological and medical sciences</topic><topic>Biosynthesis</topic><topic>Chaetomium</topic><topic>Chaetomium - chemistry</topic><topic>Chaetomium - metabolism</topic><topic>Chemistry</topic><topic>Chemistry; Biosynthesis</topic><topic>Drug Synergism</topic><topic>Enzyme Inhibitors</topic><topic>Enzyme Inhibitors - pharmacology</topic><topic>Fermentation</topic><topic>Heterocyclic Compounds, 3-Ring</topic><topic>Heterocyclic Compounds, 3-Ring - pharmacology</topic><topic>Kinetics</topic><topic>Medical sciences</topic><topic>Meropenem</topic><topic>Microbial Sensitivity Tests</topic><topic>Models, Molecular</topic><topic>Pharmacology. Drug treatments</topic><topic>Thienamycins - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>PAYNE, David J</creatorcontrib><creatorcontrib>HUESO-RODRIGUEZ, Juan Antonio</creatorcontrib><creatorcontrib>RITTENHOUSE, Stephen</creatorcontrib><creatorcontrib>TEW, David</creatorcontrib><creatorcontrib>DIEZ, Emilio</creatorcontrib><creatorcontrib>PEREZ, Paloma</creatorcontrib><creatorcontrib>DE LA FUENTE, Jesus</creatorcontrib><creatorcontrib>REES, Michael</creatorcontrib><creatorcontrib>RIVERA-SAGREDO, Alfonso</creatorcontrib><creatorcontrib>BODY, Helen</creatorcontrib><creatorcontrib>CONCHA, Néstor O</creatorcontrib><creatorcontrib>JANSON, Cheryl A</creatorcontrib><creatorcontrib>GILPIN, Martin</creatorcontrib><creatorcontrib>BATESON, John H</creatorcontrib><creatorcontrib>CHEEVER, Christy</creatorcontrib><creatorcontrib>NICONOVICH, Nancy L</creatorcontrib><creatorcontrib>PEARSON, Stewart</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Antimicrobial Agents and Chemotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PAYNE, David J</au><au>HUESO-RODRIGUEZ, Juan Antonio</au><au>RITTENHOUSE, Stephen</au><au>TEW, David</au><au>DIEZ, Emilio</au><au>PEREZ, Paloma</au><au>DE LA FUENTE, Jesus</au><au>REES, Michael</au><au>RIVERA-SAGREDO, Alfonso</au><au>BODY, Helen</au><au>CONCHA, Néstor O</au><au>JANSON, Cheryl A</au><au>GILPIN, Martin</au><au>BATESON, John H</au><au>CHEEVER, Christy</au><au>NICONOVICH, Nancy L</au><au>PEARSON, Stewart</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases</atitle><jtitle>Antimicrobial Agents and Chemotherapy</jtitle><stitle>AAC</stitle><addtitle>Antimicrob Agents Chemother</addtitle><date>2002-06-01</date><risdate>2002</risdate><volume>46</volume><issue>6</issue><spage>1880</spage><epage>1886</epage><pages>1880-1886</pages><issn>0066-4804</issn><eissn>1098-6596</eissn><coden>AACHAX</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>12019104</pmid><doi>10.1128/AAC.46.6.1880-1886.2002</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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source | American Society for Microbiology Journals; PubMed Central |
subjects | Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacillus - drug effects Bacillus cereus - drug effects Bacillus cereus - enzymology beta-Lactamase Inhibitors beta-Lactamases - metabolism Binding Sites Biological and medical sciences Biosynthesis Chaetomium Chaetomium - chemistry Chaetomium - metabolism Chemistry Chemistry Biosynthesis Drug Synergism Enzyme Inhibitors Enzyme Inhibitors - pharmacology Fermentation Heterocyclic Compounds, 3-Ring Heterocyclic Compounds, 3-Ring - pharmacology Kinetics Medical sciences Meropenem Microbial Sensitivity Tests Models, Molecular Pharmacology. Drug treatments Thienamycins - pharmacology |
title | Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases |
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