Ziprasidone therapy for post-traumatic stress disorder

We describe the cases of 2 men with chronic combat-induced post-traumatic stress disorder (PTSD) who benefited from therapy with ziprasidone. They did not have active psychotic symptoms. Both the patients had a history of inadequate response to previous trials of different psychotropic agents. Zipra...

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Bibliographic Details
Published in:Journal of psychiatry & neuroscience 2005-11, Vol.30 (6), p.430-431
Main Authors: SIDDIQUI, Zakaria, MARCIL, William A, BHATIA, Subhash C, RAMASWAMY, Sriram, PETTY, Frederick
Format: Article
Language:English
Subjects:
Antipsychotic Agents - therapeutic use
Antipsychotics
Biological and medical sciences
Brief Report
Combat Disorders - drug therapy
Combat Disorders - psychology
Drug therapy
Evaluation
Fundamental and applied biological sciences. Psychology
Humans
Male
Medical sciences
Medical treatment
Middle Aged
Piperazines - therapeutic use
Post traumatic stress disorder
Psychoanalysis
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Psychopathology. Psychiatry
Stress Disorders, Post-Traumatic - drug therapy
Stress Disorders, Post-Traumatic - psychology
Thiazoles - therapeutic use
Ziprasidone
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Summary:We describe the cases of 2 men with chronic combat-induced post-traumatic stress disorder (PTSD) who benefited from therapy with ziprasidone. They did not have active psychotic symptoms. Both the patients had a history of inadequate response to previous trials of different psychotropic agents. Ziprasidone was considered because of its broad-spectrum actions on various neurotransmitters. To our knowledge, this is the first published report of the usefulness of ziprasidone in the pharmacotherapy of PTSD, although atypical antipsychotic agents (e.g., olanzapine, quetiapine and risperidone) have been reported to be beneficial in the treatment of this condition.
ISSN:1180-4882
1488-2434