Protective effect of immunoglobulins in serum and milk of sows exposed to transmissible gastroenteritis virus

Experimental exposure of susceptible pregnant sows by various routes to the gut-origin transmissible gastroenteritis virus stimulated production of milk and serum antibodies. These antibodies neutralized the cytopathic effect of transmissible gastroenteritis virus propagated in cell culture. This in...

Full description

Saved in:
Bibliographic Details
Published in:Canadian journal of comparative medicine 1975, Vol.39 (1), p.41-45
Main Authors: Abou-Youssef, M.H, Ristic, M
Format: Article
Language:English
Subjects:
Animals
Animals, Newborn
Antibodies, Viral - analysis
Chromatography, DEAE-Cellulose
Chromatography, Gel
Coronaviridae - immunology
Dose-Response Relationship, Drug
Female
Gastroenteritis, Transmissible, of Swine - immunology
Immunization, Passive
Immunoglobulin M - analysis
Immunoglobulins
Milk - immunology
Neutralization Tests
Pregnancy
Swine
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Experimental exposure of susceptible pregnant sows by various routes to the gut-origin transmissible gastroenteritis virus stimulated production of milk and serum antibodies. These antibodies neutralized the cytopathic effect of transmissible gastroenteritis virus propagated in cell culture. This in vitro neutralizing antibody resided in the IgG and IgA immunoglobulin classes. On the other hand, protection for baby pigs resided in the IgA class of milk immunoglobulin of sows exposed orally or intramammarily but not of sows exposed intramuscularly to the virus.
ISSN:0008-4050