Role of joint afferents in motor control exemplified by effects on reflex pathways from Ib afferents

• Published in: The Journal of physiology 1978-11, Vol.284 (1), p.327-343
• Main Authors: Lundberg, A, Malmgren, K, Schomburg, E.D
• Format: Article
• Language: English
• Subjects: Animals; Cats; Evoked Potentials; Hindlimb - innervation; Interneurons - physiology; Joints - innervation; Motor Neurons - physiology; Muscles - innervation; Neural Inhibition; Neurons, Afferent - physiology; Reflex - physiology; Synapses - physiology; Synaptic Transmission
• ISSN: 0022-3751; 1469-7793
• DOI: 10.1113/jphysiol.1978.sp012543

1. Intracellular recording from motoneurones to hind limb muscles in the cat was used to investigate the effect of volleys in the posterior nerve to the knee joint on motoneurones and on transmission from Ib afferents. 2. Volleys in the joint nerve facilitate transmission in disynaptic and trisynaptic inhibitory and excitatory reflex pathways from Ib afferents. It is postulated that facilitation, which appears at a strength of 1.5 times threshold, is evoked, not by Ib afferents which 'contaminate' the joint nerve, but by afferents from joints receptors. 3. T;e time course of facilitation of the disynaptic Ib i.p.s.p.s in motoneurones indicates that these joint afferents have disynaptic connexions with the interneurones of the Ib inhibitory pathway. 4. A brief description is given of synaptic effects evoked in motoneurones by graded electrical stimulation of the posterior nerve to the knee joint. At low stimulus strength the effects may be evoked via interneurones of Ib reflex pathways, but some results suggest that other interneuronal paths are utilized as well. Somewhat higher strengths, but occasionally less than 2 times threshold, produce later synaptic effects presumably mediated by reflex paths from the flexor reflex afferents; it does not seem likely that the contributory afferents in the joint nerve have nociceptive function. 5. It is suggested that impulses from impulses from joint receptors can influence tension regulation from Golgi tendon organs; if these receptors are activated in the terminal phase of the movement they may contribute a purposeful decrease of tension. It is pointed out that joint receptors may have an important role in motor regulation by their effects on interneurones of the different neuronal systems controlling motoneurones.