Dysfunctional uterine bleeding

Abnormal uterine bleeding is a common, debilitating condition. Dysfunctional uterine bleeding (DUB) is the diagnosis given to women with abnormal uterine bleeding in whom no clear etiology can be identified. DUB has been observed in both ovulatory and anovulatory cycles. Medical treatments include n...

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Bibliographic Details
Published in:The Western journal of medicine 1998-11, Vol.169 (5), p.280-284
Main Authors: Chen, B H, Giudice, L C
Format: Article
Language:English
Subjects:
Adolescent
Adult
Anti-Inflammatory Agents, Non-Steroidal - adverse effects
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Antifibrinolytic Agents - adverse effects
Antifibrinolytic Agents - therapeutic use
Causes of
Contraceptives, Oral - adverse effects
Contraceptives, Oral - therapeutic use
Danazol - adverse effects
Danazol - therapeutic use
Diagnosis
Dysmenorrhea
Endometrium - surgery
Estrogen Antagonists - adverse effects
Estrogen Antagonists - therapeutic use
Female
Gonadotropin-Releasing Hormone - agonists
Humans
Hysterectomy
Menorrhagia - diagnosis
Menorrhagia - drug therapy
Menorrhagia - surgery
Menorrhagia - therapy
Middle Aged
Ovulation - physiology
Patient Satisfaction
Progestins - adverse effects
Progestins - therapeutic use
Surgery
Treatment Outcome
Uterine bleeding
Uterus
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Summary:Abnormal uterine bleeding is a common, debilitating condition. Dysfunctional uterine bleeding (DUB) is the diagnosis given to women with abnormal uterine bleeding in whom no clear etiology can be identified. DUB has been observed in both ovulatory and anovulatory cycles. Medical treatments include nonsteroidal anti-inflammatory drugs, oral contraceptive pills, progestins, danazol (a synthetic androgen), GnRH agonists, and antifibrinolytic drugs. The drawback to medical therapy, in addition to side effects, is that the benefit lasts only while the patient takes the medication. Surgical options have concentrated mainly on endometrial ablation and hysterectomy, and it is unclear whether one is superior to the other in terms of long-term outcome and patient satisfaction. Newer and less invasive ablation techniques, such as thermal balloon ablation, offer more treatment alternatives.
ISSN:0093-0415
1476-2978