Rubeosis iridis generated by insulin hypersensitivity

There are important similarities between human and experimental monkey rubeosis iridis. We believe that we have developed a useful primate model to study iris neovascularization and that the possible role of immunity to insulin in the pathogenesis of human diabetic rubeosis iridis warrants further d...

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Bibliographic Details
Published in:Transactions of the American Ophthalmological Society 1976, Vol.74, p.203-219
Main Authors: Shabo, A L, Maxwell, D S, Kreiger, A E, Straatsma, B R
Format: Article
Language:English
Subjects:
Animals
Blood Vessels - pathology
Diabetes Mellitus - drug therapy
Disease Models, Animal
Drug Hypersensitivity - complications
Haplorhini
Humans
Hyperemia - immunology
Immunization
Inflammation - immunology
Insulin - adverse effects
Iris - blood supply
Iris - pathology
Macaca mulatta
Uveal Diseases - immunology
Uveal Diseases - pathology
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Summary:There are important similarities between human and experimental monkey rubeosis iridis. We believe that we have developed a useful primate model to study iris neovascularization and that the possible role of immunity to insulin in the pathogenesis of human diabetic rubeosis iridis warrants further detailed consideration.
ISSN:0065-9533
1545-6110