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Effects of stimulation of efferent fibres of the vagus on the reticulo-omasal orifice of the sheep
1. The reticulo-omasal orifice has been observed and its activity recorded in decerebrate and spinal preparations of lambs and in lambs and sheep anaesthetized with chloralose. 2. Spontaneous closure movements at about 6/min were seen, or recorded from balloons placed in the orifice in all types of...
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| Published in: | The Journal of physiology 1972-04, Vol.222 (2), p.407-418 |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
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| container_end_page | 418 |
| container_issue | 2 |
| container_start_page | 407 |
| container_title | The Journal of physiology |
| container_volume | 222 |
| creator | Newhook, J. C. Titchen, D. A. |
| description | 1. The reticulo-omasal orifice has been observed and its activity recorded in decerebrate and spinal preparations of lambs
and in lambs and sheep anaesthetized with chloralose.
2. Spontaneous closure movements at about 6/min were seen, or recorded from balloons placed in the orifice in all types of
preparation when both vagus nerves had been cut and after atropine, hexamethonium, phentolamine and propranolol had been given
I.V.
3. The effects on the reticulo-omasal orifice of stimulation in the neck of efferent fibres of the vagus nerves on either
side differed according to the form of the stimulus applied.
4. Threshold stimulation of the vagus nerve caused closing of the orifice which was blocked by atropine.
5. Opening of the orifice and disappearance of spontaneous closing movements followed more intense stimulation of the vagus
nerves.
6. Vagal opening effects were obtained after atropine was given and after adrenergic opening and closure effects had been
blocked with phentolamine and propranolol. |
| doi_str_mv | 10.1113/jphysiol.1972.sp009805 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1331389</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>81480421</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5007-169ca6f169d56c77f98eff2b25fa904ba898adcb5ffa12309a6e01edee137c753</originalsourceid><addsrcrecordid>eNqNUU1v1DAQtRCoLIWfAMoJTlk8cRLHFySoCi2qBIdythzveOPKiYOdtNp_j9PsVnDDl9H4ffhZj5B3QLcAwD7ejd0hWu-2IHixjSOloqHVM7KBshY554I9JxtKiyJnvIKX5FWMd5QCo0KckbOKMlZy2JD20hjUU8y8yeJk-9mpyfphWTEhAYcpM7YN-MiYOszu1X5Oy_C4BJysnp3Pfa-icpkP1liNJ27sEMfX5IVRLuKb4zwnv75e3l5c5Tc_vl1ffL7JdUUpz6EWWtUmjV1Va86NaFKCoi0qowQtW9WIRu10WxmjoEj_UDVSwB0iMK55xc7Jp9V3nNsedzpFD8rJMdhehYP0ysp_kcF2cu_vJTAGrBHJ4P3RIPjfM8ZJ9jZqdE4N6OcoGygbWhaQiPVK1MHHGNA8PQJULu3IUztyaUee2knCt39HfJId60j4lxV_sA4P_-kqb7__XC6WU1KeTD6sJp3ddw82oFxl0WuL00EmmizkwvwDjVmz9w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>81480421</pqid></control><display><type>article</type><title>Effects of stimulation of efferent fibres of the vagus on the reticulo-omasal orifice of the sheep</title><source>PubMed Central</source><creator>Newhook, J. C. ; Titchen, D. A.</creator><creatorcontrib>Newhook, J. C. ; Titchen, D. A.</creatorcontrib><description>1. The reticulo-omasal orifice has been observed and its activity recorded in decerebrate and spinal preparations of lambs
and in lambs and sheep anaesthetized with chloralose.
2. Spontaneous closure movements at about 6/min were seen, or recorded from balloons placed in the orifice in all types of
preparation when both vagus nerves had been cut and after atropine, hexamethonium, phentolamine and propranolol had been given
I.V.
3. The effects on the reticulo-omasal orifice of stimulation in the neck of efferent fibres of the vagus nerves on either
side differed according to the form of the stimulus applied.
4. Threshold stimulation of the vagus nerve caused closing of the orifice which was blocked by atropine.
5. Opening of the orifice and disappearance of spontaneous closing movements followed more intense stimulation of the vagus
nerves.
6. Vagal opening effects were obtained after atropine was given and after adrenergic opening and closure effects had been
blocked with phentolamine and propranolol.</description><identifier>ISSN: 0022-3751</identifier><identifier>EISSN: 1469-7793</identifier><identifier>DOI: 10.1113/jphysiol.1972.sp009805</identifier><identifier>PMID: 5033471</identifier><language>eng</language><publisher>England: The Physiological Society</publisher><subject>Animals ; Atropine - pharmacology ; Blood Pressure ; Electric Stimulation ; Evoked Potentials ; Hexamethonium Compounds - pharmacology ; Muscle Contraction - drug effects ; Neurons, Efferent - physiology ; Omasum - innervation ; Omasum - physiology ; Phentolamine - pharmacology ; Propranolol - pharmacology ; Reticulum - innervation ; Reticulum - physiology ; Sheep ; Vagus Nerve - drug effects ; Vagus Nerve - physiology</subject><ispartof>The Journal of physiology, 1972-04, Vol.222 (2), p.407-418</ispartof><rights>1972 The Physiological Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5007-169ca6f169d56c77f98eff2b25fa904ba898adcb5ffa12309a6e01edee137c753</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1331389/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1331389/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5033471$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Newhook, J. C.</creatorcontrib><creatorcontrib>Titchen, D. A.</creatorcontrib><title>Effects of stimulation of efferent fibres of the vagus on the reticulo-omasal orifice of the sheep</title><title>The Journal of physiology</title><addtitle>J Physiol</addtitle><description>1. The reticulo-omasal orifice has been observed and its activity recorded in decerebrate and spinal preparations of lambs
and in lambs and sheep anaesthetized with chloralose.
2. Spontaneous closure movements at about 6/min were seen, or recorded from balloons placed in the orifice in all types of
preparation when both vagus nerves had been cut and after atropine, hexamethonium, phentolamine and propranolol had been given
I.V.
3. The effects on the reticulo-omasal orifice of stimulation in the neck of efferent fibres of the vagus nerves on either
side differed according to the form of the stimulus applied.
4. Threshold stimulation of the vagus nerve caused closing of the orifice which was blocked by atropine.
5. Opening of the orifice and disappearance of spontaneous closing movements followed more intense stimulation of the vagus
nerves.
6. Vagal opening effects were obtained after atropine was given and after adrenergic opening and closure effects had been
blocked with phentolamine and propranolol.</description><subject>Animals</subject><subject>Atropine - pharmacology</subject><subject>Blood Pressure</subject><subject>Electric Stimulation</subject><subject>Evoked Potentials</subject><subject>Hexamethonium Compounds - pharmacology</subject><subject>Muscle Contraction - drug effects</subject><subject>Neurons, Efferent - physiology</subject><subject>Omasum - innervation</subject><subject>Omasum - physiology</subject><subject>Phentolamine - pharmacology</subject><subject>Propranolol - pharmacology</subject><subject>Reticulum - innervation</subject><subject>Reticulum - physiology</subject><subject>Sheep</subject><subject>Vagus Nerve - drug effects</subject><subject>Vagus Nerve - physiology</subject><issn>0022-3751</issn><issn>1469-7793</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><recordid>eNqNUU1v1DAQtRCoLIWfAMoJTlk8cRLHFySoCi2qBIdythzveOPKiYOdtNp_j9PsVnDDl9H4ffhZj5B3QLcAwD7ejd0hWu-2IHixjSOloqHVM7KBshY554I9JxtKiyJnvIKX5FWMd5QCo0KckbOKMlZy2JD20hjUU8y8yeJk-9mpyfphWTEhAYcpM7YN-MiYOszu1X5Oy_C4BJysnp3Pfa-icpkP1liNJ27sEMfX5IVRLuKb4zwnv75e3l5c5Tc_vl1ffL7JdUUpz6EWWtUmjV1Va86NaFKCoi0qowQtW9WIRu10WxmjoEj_UDVSwB0iMK55xc7Jp9V3nNsedzpFD8rJMdhehYP0ysp_kcF2cu_vJTAGrBHJ4P3RIPjfM8ZJ9jZqdE4N6OcoGygbWhaQiPVK1MHHGNA8PQJULu3IUztyaUee2knCt39HfJId60j4lxV_sA4P_-kqb7__XC6WU1KeTD6sJp3ddw82oFxl0WuL00EmmizkwvwDjVmz9w</recordid><startdate>19720401</startdate><enddate>19720401</enddate><creator>Newhook, J. C.</creator><creator>Titchen, D. A.</creator><general>The Physiological Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19720401</creationdate><title>Effects of stimulation of efferent fibres of the vagus on the reticulo-omasal orifice of the sheep</title><author>Newhook, J. C. ; Titchen, D. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5007-169ca6f169d56c77f98eff2b25fa904ba898adcb5ffa12309a6e01edee137c753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Animals</topic><topic>Atropine - pharmacology</topic><topic>Blood Pressure</topic><topic>Electric Stimulation</topic><topic>Evoked Potentials</topic><topic>Hexamethonium Compounds - pharmacology</topic><topic>Muscle Contraction - drug effects</topic><topic>Neurons, Efferent - physiology</topic><topic>Omasum - innervation</topic><topic>Omasum - physiology</topic><topic>Phentolamine - pharmacology</topic><topic>Propranolol - pharmacology</topic><topic>Reticulum - innervation</topic><topic>Reticulum - physiology</topic><topic>Sheep</topic><topic>Vagus Nerve - drug effects</topic><topic>Vagus Nerve - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Newhook, J. C.</creatorcontrib><creatorcontrib>Titchen, D. A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Journal of physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Newhook, J. C.</au><au>Titchen, D. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of stimulation of efferent fibres of the vagus on the reticulo-omasal orifice of the sheep</atitle><jtitle>The Journal of physiology</jtitle><addtitle>J Physiol</addtitle><date>1972-04-01</date><risdate>1972</risdate><volume>222</volume><issue>2</issue><spage>407</spage><epage>418</epage><pages>407-418</pages><issn>0022-3751</issn><eissn>1469-7793</eissn><abstract>1. The reticulo-omasal orifice has been observed and its activity recorded in decerebrate and spinal preparations of lambs
and in lambs and sheep anaesthetized with chloralose.
2. Spontaneous closure movements at about 6/min were seen, or recorded from balloons placed in the orifice in all types of
preparation when both vagus nerves had been cut and after atropine, hexamethonium, phentolamine and propranolol had been given
I.V.
3. The effects on the reticulo-omasal orifice of stimulation in the neck of efferent fibres of the vagus nerves on either
side differed according to the form of the stimulus applied.
4. Threshold stimulation of the vagus nerve caused closing of the orifice which was blocked by atropine.
5. Opening of the orifice and disappearance of spontaneous closing movements followed more intense stimulation of the vagus
nerves.
6. Vagal opening effects were obtained after atropine was given and after adrenergic opening and closure effects had been
blocked with phentolamine and propranolol.</abstract><cop>England</cop><pub>The Physiological Society</pub><pmid>5033471</pmid><doi>10.1113/jphysiol.1972.sp009805</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3751 |
| ispartof | The Journal of physiology, 1972-04, Vol.222 (2), p.407-418 |
| issn | 0022-3751 1469-7793 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1331389 |
| source | PubMed Central |
| subjects | Animals Atropine - pharmacology Blood Pressure Electric Stimulation Evoked Potentials Hexamethonium Compounds - pharmacology Muscle Contraction - drug effects Neurons, Efferent - physiology Omasum - innervation Omasum - physiology Phentolamine - pharmacology Propranolol - pharmacology Reticulum - innervation Reticulum - physiology Sheep Vagus Nerve - drug effects Vagus Nerve - physiology |
| title | Effects of stimulation of efferent fibres of the vagus on the reticulo-omasal orifice of the sheep |
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