Irradiation induced salivary gland neoplasia

Twenty-six patients with a prior history of irradiation for benign conditions of the head and neck and salivary gland abnormalities are reported. All the patients had preoperative physical findings suggestive of tumor, not glandular infection. Forty-six per cent of the patients had one carcinoma and...

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Bibliographic Details
Published in:Annals of surgery 1980-03, Vol.191 (3), p.304-306
Main Authors: Sener, S F, Scanlon, E F
Format: Article
Language:English
Subjects:
Female
Humans
Male
Metaplasia
Middle Aged
Neoplasms, Radiation-Induced - etiology
Parotid Neoplasms - etiology
Radiotherapy - adverse effects
Salivary Gland Neoplasms - etiology
Submandibular Gland
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Summary:Twenty-six patients with a prior history of irradiation for benign conditions of the head and neck and salivary gland abnormalities are reported. All the patients had preoperative physical findings suggestive of tumor, not glandular infection. Forty-six per cent of the patients had one carcinoma and 11% had two carcinomas within the irradiated field. Eight of the 11 malignant tumors in these 26 patients were in the parotid gland. The nonmalignant salivery changes were similar to those previously reported in glands receiving therapeutic irradiation for carcinoma.
ISSN:0003-4932
1528-1140
DOI:10.1097/00000658-198003000-00008