LIFEdb database in 2006

LIFEdb (http://www.LIFEdb.de) integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New features of LIFEdb include (i) an updated user interface with enhanced query capabilities, (ii) a configurable output tab...

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Bibliographic Details
Published in:Nucleic acids research 2006-01, Vol.34 (1), p.D415-D418
Main Authors: Mehrle, Alexander, Rosenfelder, Heiko, Schupp, Ingo, del Val, Coral, Arlt, Dorit, Hahne, Florian, Bechtel, Stephanie, Simpson, Jeremy, Hofmann, Oliver, Hide, Winston, Glatting, Karl-Heinz, Huber, Wolfgang, Pepperkok, Rainer, Poustka, Annemarie, Wiemann, Stefan
Format: Article
Language:English
Subjects:
Cell Proliferation
Computational Biology
Databases, Genetic
DNA, Complementary - chemistry
Gene Expression
Genes
Genomics
Internet
Proteins - analysis
Proteins - genetics
Proteins - metabolism
Recombinant Fusion Proteins - metabolism
Systems Integration
User-Computer Interface
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Summary:LIFEdb (http://www.LIFEdb.de) integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New features of LIFEdb include (i) an updated user interface with enhanced query capabilities, (ii) a configurable output table and the option to download search results in XML, (iii) the integration of data from cell-based screening assays addressing the influence of protein-overexpression on cell proliferation and (iv) the display of the relative expression ('Electronic Northern') of the genes under investigation using curated gene expression ontology information. LIFEdb enables researchers to systematically select and characterize genes and proteins of interest, and presents data and information via its user-friendly web-based interface.
ISSN:0305-1048
1362-4962
DOI:10.1093/nar/gkj139