Survival analysis of hemophilia-associated AIDS cases in the US

Using national hemophilia-associated AIDS (acquired immunodeficiency syndrome) surveillance data and the life table method of survival analysis, the median length of survival of hemophilic patients in the United States after the diagnosis of AIDS was 11.7 months; the cumulative probability of surviv...

Full description

Saved in:
Bibliographic Details
Published in:American journal of public health (1971) 1989-07, Vol.79 (7), p.832-835
Main Authors: Stehr-Green, J K, Holman, R C, Mahoney, M A
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Acquired Immunodeficiency Syndrome - complications
Acquired Immunodeficiency Syndrome - diagnosis
Acquired Immunodeficiency Syndrome - mortality
Adolescent
Adult
Age Factors
AIDS
AIDS/HIV
Biological and medical sciences
Child
Death & dying
Female
Hematologic and hematopoietic diseases
Hemophilia
Hemophilia A - complications
Hemophilia A - mortality
Humans
Male
Medical research
Medical sciences
Middle Aged
Platelet diseases and coagulopathies
Population Surveillance
Public health
Risk Factors
Surveillance
Survival analysis
Time Factors
United States
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Using national hemophilia-associated AIDS (acquired immunodeficiency syndrome) surveillance data and the life table method of survival analysis, the median length of survival of hemophilic patients in the United States after the diagnosis of AIDS was 11.7 months; the cumulative probability of survival at one year was 49.2 +/- 2.0 percent; at two years, 28.9 +/- 2.3 percent. Patients 13-29 years of age at the time of diagnosis had the longest survival and those 60 years and older had the shortest. Patients diagnosed since 1986 survived longer than those diagnosed before 1986. Length of survival did not differ significantly by race, coagulation disorder, AIDS manifestation at the time of diagnosis, or region of residence. Seven patients survived more than 36 months after AIDS was diagnosed. These patients were similar to those surviving for a shorter duration except that they were more likely to have met only the 1987 revision of the Centers for Disease Control AIDS surveillance case definition (as opposed to the 1985 case definition). Results of this study suggest that survival among hemophilic patients after the diagnosis of AIDS is similar to that reported by other investigators for other AIDS risk groups, excluding patients with Kaposi's sarcoma.
ISSN:0090-0036
1541-0048
DOI:10.2105/AJPH.79.7.832