Levels of salivary IgA in treated and untreated coeliac disease

Estimations of the concentration of secretory IgA have been performed on 152 specimens of saliva from 46 patients with adult coeliac disease. The results are compared with values observed in 20 normal subjects. The mean salivary IgA concentration was 9 mg% in 36 patients on a normal diet and 7·9 mg%...

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Bibliographic Details
Published in:Gut 1972-09, Vol.13 (9), p.718-720
Main Authors: Wallington, T., Ajdukiewicz, A. B., Read, A. E., Jones, J. Verrier
Format: Article
Language:English
Subjects:
Celiac Disease - immunology
Celiac Disease - therapy
Diet
Diet Therapy
Glutens
Humans
Immunodiffusion
Immunoglobulin A - analysis
Saliva - analysis
Saliva - immunology
Salivary Glands - immunology
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Summary:Estimations of the concentration of secretory IgA have been performed on 152 specimens of saliva from 46 patients with adult coeliac disease. The results are compared with values observed in 20 normal subjects. The mean salivary IgA concentration was 9 mg% in 36 patients on a normal diet and 7·9 mg% in 21 patients on a gluten-free diet. In 20 normals the mean salivary IgA was 7·1 mg%. Nine patients were studied before and after gluten exclusion. Seven of these showed a marked fall in salivary IgA concentration after gluten was excluded.
ISSN:0017-5749
1468-3288
1458-3288
DOI:10.1136/gut.13.9.718