Studies on the stability of vitamin A in the stomach and small intestine

The instability of vitamin A alcohol relative to vitamin A acetate has been studied in vivo and in vitro. Vitamin A alcohol is more unstable than vitamin A acetate in human gastric and duodenal juice and in rats' stomachs and intestines and is more marked at lower pH levels and in rats' st...

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Published in:Gut 1962-09, Vol.3 (3), p.264-266
Main Authors: Fitzgerald, Oliver, Fennelly, James J., Hingerty, Daniel J.
Format: Article
Language:English
Subjects:
Animals
Gastric Juice
Humans
Intestine, Small
Intestines
Male
Old Medline
Rats
Stomach
Vitamin A
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cited_by cdi_FETCH-LOGICAL-b476t-c3c70531ce774d540997145a91284fbcd609f62a939a95d61b5100ac05ed8d463
cites cdi_FETCH-LOGICAL-b476t-c3c70531ce774d540997145a91284fbcd609f62a939a95d61b5100ac05ed8d463
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container_title Gut
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creator Fitzgerald, Oliver
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description The instability of vitamin A alcohol relative to vitamin A acetate has been studied in vivo and in vitro. Vitamin A alcohol is more unstable than vitamin A acetate in human gastric and duodenal juice and in rats' stomachs and intestines and is more marked at lower pH levels and in rats' stomachs. Alpha tocopherol improved the absorption curve of vitamin A alcohol in man by protecting it in gastric and duodenal juice. This protective effect could not be demonstrated in the rat.
doi_str_mv 10.1136/gut.3.3.264
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subjects Animals
Gastric Juice
Humans
Intestine, Small
Intestines
Male
Old Medline
Rats
Stomach
Vitamin A
title Studies on the stability of vitamin A in the stomach and small intestine
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