Incidence of sulphasalazine-induced male infertility

Sperm analysis of 21 patients taking sulphasalazine for inflammatory bowel disease revealed that 86% had abnormal semen analysis and 72% had oligospermia.

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Bibliographic Details
Published in:Gut 1981-06, Vol.22 (6), p.452-455
Main Authors: Birnie, G G, McLeod, T I, Watkinson, G
Format: Article
Language:English
Subjects:
Adolescent
Adult
Colitis, Ulcerative - drug therapy
Crohn Disease - drug therapy
Humans
Infertility, Male - chemically induced
Infertility, Male - epidemiology
Male
Middle Aged
Spermatozoa - drug effects
Sulfasalazine - adverse effects
Sulfasalazine - therapeutic use
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Description
Summary:Sperm analysis of 21 patients taking sulphasalazine for inflammatory bowel disease revealed that 86% had abnormal semen analysis and 72% had oligospermia.
ISSN:0017-5749
1468-3288
1458-3288
DOI:10.1136/gut.22.6.452