Resection of hepatocellular carcinoma in patients otherwise eligible for transplantation

The incidence of hepatocellular carcinoma (HCC) in the United States has increased 75% in the last decade. Liver transplantation is gaining acceptance for the treatment of early HCC, even in patients with adequate liver function. The objective of this study was to determine the long-term outcome of...

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Bibliographic Details
Published in:Annals of surgery 2003-09, Vol.238 (3), p.315-323
Main Authors: Cha, Charles H, Ruo, Leyo, Fong, Yuman, Jarnagin, William R, Shia, Jinru, Blumgart, Leslie H, DeMatteo, Ronald P
Format: Article
Language:English
Subjects:
Aged
Carcinoma, Hepatocellular - epidemiology
Carcinoma, Hepatocellular - surgery
Databases, Factual - statistics & numerical data
Female
Follow-Up Studies
Hepatectomy - methods
Humans
Incidence
Length of Stay - statistics & numerical data
Liver - physiology
Liver Cirrhosis - epidemiology
Liver Neoplasms - epidemiology
Liver Neoplasms - surgery
Liver Transplantation
Male
Original Papers and Discussions
Survival Analysis
Survival Rate
Time Factors
United States - epidemiology
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Summary:The incidence of hepatocellular carcinoma (HCC) in the United States has increased 75% in the last decade. Liver transplantation is gaining acceptance for the treatment of early HCC, even in patients with adequate liver function. The objective of this study was to determine the long-term outcome of patients with early HCC who would have been candidates for transplantation but were treated instead with partial hepatectomy. From August 1989 to November 2001, 611 patients with HCC were evaluated at our institution and entered into a prospective database. There were 180 (29%) patients who underwent partial hepatectomy, of whom 36 (20%) satisfied the currently accepted criteria for transplantation: 2 or 3 lesions each
ISSN:0003-4932
1528-1140
DOI:10.1097/01.sla.0000086548.84705.ef