Clustering of adenomas in the large intestine

In a necropsy study of 68 men and 36 women with single or multiple adenomas of the large intestine the distribution of all adenomas within the bowel in individual patients was examined. Each adenoma was recorded both by its distance in centimetres from the caecal pole and by the intestinal segment i...

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Bibliographic Details
Published in:Gut 1984-11, Vol.25 (11), p.1262-1267
Main Authors: Eide, T J, Schweder, T
Format: Article
Language:English
Subjects:
Adenoma - pathology
Adult
Age Factors
Aged
Biological and medical sciences
Colonic Neoplasms - pathology
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Male
Medical sciences
Middle Aged
Rectal Neoplasms - pathology
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tumors
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Summary:In a necropsy study of 68 men and 36 women with single or multiple adenomas of the large intestine the distribution of all adenomas within the bowel in individual patients was examined. Each adenoma was recorded both by its distance in centimetres from the caecal pole and by the intestinal segment in which it was found. Adenomas in individual patients were shown to occur significantly closer together than expected from the general distribution of adenomas within each age group. The statistically significant, but not very strong effect of clustering may be caused by the existence of one or more fields of the large intestine specific to individuals who have a higher than average propensity for neoplastic development.
ISSN:0017-5749
1468-3288
1458-3288
DOI:10.1136/gut.25.11.1262