Specific food intolerance: its place as a cause of gastrointestinal symptoms

Thirteen out of 49 patients suspected of having specific food intolerance after withdrawal and reintroduction of specific foods, were further subjected to double blind placebo controlled food challenges. Only three of these subjects were thus shown to have proven specific food intolerance. Of the re...

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Bibliographic Details
Published in:Gut 1985-02, Vol.26 (2), p.164-168
Main Authors: Farah, D A, Calder, I, Benson, L, MacKenzie, J F
Format: Article
Language:English
Subjects:
Adult
Allergic diseases
Biological and medical sciences
Digestive allergic diseases
Double-Blind Method
Female
Follow-Up Studies
Food Hypersensitivity - complications
Food Hypersensitivity - diagnosis
Food Hypersensitivity - psychology
Gastrointestinal Diseases - etiology
Humans
Immunopathology
Male
Medical sciences
Middle Aged
Radioallergosorbent Test
Skin Tests
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Summary:Thirteen out of 49 patients suspected of having specific food intolerance after withdrawal and reintroduction of specific foods, were further subjected to double blind placebo controlled food challenges. Only three of these subjects were thus shown to have proven specific food intolerance. Of the remaining 10, nine were strong 'placebo reactors'. The study suggests that a small number of patients with gastrointestinal symptoms have verifiable specific food intolerance but that a greater number have symptoms attributable to psychogenic causes.
ISSN:0017-5749
1468-3288
1458-3288
DOI:10.1136/gut.26.2.164