Risk of breast cancer in women with history of benign disease of the breast

A consecutive series of 791 women who had attended diagnostic breast clinics during 1967-70 and been found to be free of malignant disease were later traced to determine their subsequent incidence of breast cancer. Of the 770 (97%) successfully traced, 22 had developed breast cancer. Based on data f...

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Published in:BMJ 1984-01, Vol.288 (6413), p.275-278
Main Authors: Roberts, M M, Jones, V, Elton, R A, Fortt, R W, Williams, S, Gravelle, I H
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age groups
Aged
Biological and medical sciences
Biopsies
Breast cancer
Breast Neoplasms - epidemiology
Breast Neoplasms - pathology
Cancer
Disease risk
Epidemiology
Female
Gynecology. Andrology. Obstetrics
Humans
Hyperplasia
Mammary gland diseases
Mammography
Medical sciences
Middle Aged
Mortality
Pathology
Predisposing factors
Risk
Tumors
Wales
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container_issue 6413
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creator Roberts, M M
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description A consecutive series of 791 women who had attended diagnostic breast clinics during 1967-70 and been found to be free of malignant disease were later traced to determine their subsequent incidence of breast cancer. Of the 770 (97%) successfully traced, 22 had developed breast cancer. Based on data from the Welsh Cancer Registry only eight cases of breast cancer had been expected, so that the excess risk for the group was 2.7. The increased risk occurred in all age groups and in women deemed "essentially normal" as well as in those who had had a pathological abnormality. The risk was increased when epithelial hyperplasia was present. No excess mortality from breast cancer was apparent, but follow up was short. More breast symptoms were experienced and more biopsies performed than expected in this group of women. Women with a past history of benign breast disease have a slightly increased risk of breast cancer. Selective screening of these women, however, may be uneconomic and a cause of groundless anxiety.
doi_str_mv 10.1136/bmj.288.6413.275
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identifier ISSN: 0007-1447
ispartof BMJ, 1984-01, Vol.288 (6413), p.275-278
issn 0007-1447
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source JSTOR Archival Journals; BMJ Journals; PubMed Central
subjects Adolescent
Adult
Age groups
Aged
Biological and medical sciences
Biopsies
Breast cancer
Breast Neoplasms - epidemiology
Breast Neoplasms - pathology
Cancer
Disease risk
Epidemiology
Female
Gynecology. Andrology. Obstetrics
Humans
Hyperplasia
Mammary gland diseases
Mammography
Medical sciences
Middle Aged
Mortality
Pathology
Predisposing factors
Risk
Tumors
Wales
title Risk of breast cancer in women with history of benign disease of the breast
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