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Lymphocyte nucleoli activation as a marker of autoimmune disorder development. I. Observation in NZB mice

An increased number of lymphocytes with nucleoli synthesizing RNA was found in blood and lymph nodes of aged NZB mice who developed an autoimmune disease. This was not observed in young NZB mice and in 40NX mice where no immune disorders were noted.

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Published in:Immunology 1976-04, Vol.30 (4), p.475-477
Main Authors: Korcáková, L, Rovenský, J, Pekárek, J, Haskova, V
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Language:English
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container_title Immunology
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creator Korcáková, L
Rovenský, J
Pekárek, J
Haskova, V
description An increased number of lymphocytes with nucleoli synthesizing RNA was found in blood and lymph nodes of aged NZB mice who developed an autoimmune disease. This was not observed in young NZB mice and in 40NX mice where no immune disorders were noted.
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ispartof Immunology, 1976-04, Vol.30 (4), p.475-477
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source Open Access: PubMed Central
subjects Age Factors
Animals
Autoimmune Diseases - blood
Cell Nucleolus - metabolism
Leukocyte Count
Lymph Nodes
Lymphocyte Activation
Lymphocytes - metabolism
Lymphocytes - ultrastructure
Mice
Mice, Inbred NZB - immunology
RNA - biosynthesis
title Lymphocyte nucleoli activation as a marker of autoimmune disorder development. I. Observation in NZB mice
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