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Lymphocyte nucleoli activation as a marker of autoimmune disorder development. I. Observation in NZB mice
An increased number of lymphocytes with nucleoli synthesizing RNA was found in blood and lymph nodes of aged NZB mice who developed an autoimmune disease. This was not observed in young NZB mice and in 40NX mice where no immune disorders were noted.
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Published in: | Immunology 1976-04, Vol.30 (4), p.475-477 |
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container_end_page | 477 |
container_issue | 4 |
container_start_page | 475 |
container_title | Immunology |
container_volume | 30 |
creator | Korcáková, L Rovenský, J Pekárek, J Haskova, V |
description | An increased number of lymphocytes with nucleoli synthesizing RNA was found in blood and lymph nodes of aged NZB mice who developed an autoimmune disease. This was not observed in young NZB mice and in 40NX mice where no immune disorders were noted. |
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I. Observation in NZB mice</title><title>Immunology</title><addtitle>Immunology</addtitle><description>An increased number of lymphocytes with nucleoli synthesizing RNA was found in blood and lymph nodes of aged NZB mice who developed an autoimmune disease. This was not observed in young NZB mice and in 40NX mice where no immune disorders were noted.</description><subject>Age Factors</subject><subject>Animals</subject><subject>Autoimmune Diseases - blood</subject><subject>Cell Nucleolus - metabolism</subject><subject>Leukocyte Count</subject><subject>Lymph Nodes</subject><subject>Lymphocyte Activation</subject><subject>Lymphocytes - metabolism</subject><subject>Lymphocytes - ultrastructure</subject><subject>Mice</subject><subject>Mice, Inbred NZB - immunology</subject><subject>RNA - biosynthesis</subject><issn>0019-2805</issn><issn>1365-2567</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1976</creationdate><recordtype>article</recordtype><recordid>eNpVkE1PwzAMhiMEGmPwE5By4tbJbdo0vSAB4mPSxC5w4VK5qcsCTVOadtL-PZGYEJwsv7af1_YRm8dCZlGSyfyYzQHiIkoUZKfszPuPkArIshmbxUkOoNI5M-u97bdO70fi3aRbcq3hqEezw9G4jqPnyC0OnzRw13CcRmesnTritfFuqINc045a11vqxiVfLfmm8jQcxk3Hn99uuTWaztlJg62ni0NcsNeH-5e7p2i9eVzd3ayjPgYlI9FIAXktJZBqcsCiEqpoEBpQgELHOqhaVxmE7irOSRYVpjqXhHUGIgGxYNc_3H6qLNU6rDVgW_aDCWfsS4em_F_pzLZ8d7syTtNAlQFwdQAM7msiP5bWeE1tix25yZdKpEIqpULj5V-nX4vDc8U3WUd42g</recordid><startdate>197604</startdate><enddate>197604</enddate><creator>Korcáková, L</creator><creator>Rovenský, J</creator><creator>Pekárek, J</creator><creator>Haskova, V</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>197604</creationdate><title>Lymphocyte nucleoli activation as a marker of autoimmune disorder development. 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ispartof | Immunology, 1976-04, Vol.30 (4), p.475-477 |
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language | eng |
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source | Open Access: PubMed Central |
subjects | Age Factors Animals Autoimmune Diseases - blood Cell Nucleolus - metabolism Leukocyte Count Lymph Nodes Lymphocyte Activation Lymphocytes - metabolism Lymphocytes - ultrastructure Mice Mice, Inbred NZB - immunology RNA - biosynthesis |
title | Lymphocyte nucleoli activation as a marker of autoimmune disorder development. I. Observation in NZB mice |
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