Increasing Latino Adolescents' Adherence to Treatment for Latent Tuberculosis Infection: A Controlled Trial

We sought to determine the efficacy of coaching Latino adolescents with latent tuberculosis infection to adhere to isoniazid treatment. Participants (n = 286) were randomly assigned to adherence coaching, attention control, or usual care groups. Adherence was measured via interviews and validated wi...

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Bibliographic Details
Published in:American journal of public health (1971) 2003-11, Vol.93 (11), p.1871-1877
Main Authors: Hovell, Melbourne F, Sipan, Carol L, Blumberg, Elaine J, Hofstetter, C. Richard, Slymen, Donald, Friedman, Lawrence, Moser, Kathleen, Kelley, Norma J, Vera, Alicia Y
Format: Article
Language:English
Subjects:
Adherence
Adolescent
Adolescent Behavior - ethnology
Adolescent Health
Antitubercular Agents - administration & dosage
Antitubercular Agents - urine
Bilingualism
Biological and medical sciences
California
Coaching
Counseling
Education
Efficacy
Female
Health care
Health Services Research
Hispanic Americans
Hispanic or Latino - psychology
Homeless people
Humans
Infections
Intervention
Interviews
Isoniazid
Isoniazid - administration & dosage
Isoniazid - urine
Latin American people
Male
Medical sciences
Medical treatment
Mexico - ethnology
Noncitizens
Patient compliance
Patient Compliance - ethnology
Premedication - psychology
Prevention
Prevention and actions
Public health
Public health. Hygiene
Public health. Hygiene-occupational medicine
Self Administration - psychology
Self Concept
Self esteem
Social Support
Specific populations (family, woman, child, elderly...)
Teenagers
Treatment
Tuberculosis
Tuberculosis - drug therapy
Tuberculosis - prevention & control
X-rays
Young people
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Description
Summary:We sought to determine the efficacy of coaching Latino adolescents with latent tuberculosis infection to adhere to isoniazid treatment. Participants (n = 286) were randomly assigned to adherence coaching, attention control, or usual care groups. Adherence was measured via interviews and validated with urine assays. Coaching resulted in significant increases in adherence compared with attention and usual care groups. Bicultural adolescents were more likely to be adherent than those most or least acculturated. Age and risk behavior were negatively related to adherence. Coaching can increase Latino adolescents' adherence to treatment for latent tuberculosis infection and should contribute to tuberculosis control for adolescents at high risk of contracting the disease.
ISSN:0090-0036
1541-0048
DOI:10.2105/AJPH.93.11.1871