Patterns of Diversity and Linkage Disequilibrium Within the Cosmopolitan Inversion In(3R)Payne in Drosophila melanogaster Are Indicative of Coadaptation

The cosmopolitan inversion In(3R)Payne in Drosophila melanogaster decreases in frequency with increasing distance from the equator on three continents, indicating it is subject to strong natural selection. We investigated patterns of genetic variation and linkage disequilibrium (LD) in 24 molecular...

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Bibliographic Details
Published in:Genetics (Austin) 2006-03, Vol.172 (3), p.1655-1663
Main Authors: Kennington, W. Jason, Partridge, Linda, Hoffmann, Ary A
Format: Article
Language:English
Subjects:
Adaptation, Biological - genetics
Animal populations
Animals
Chromosome Inversion - genetics
Confidence intervals
Data analysis
Drosophila melanogaster
Drosophila melanogaster - genetics
Female
Genes
Genetic Markers
Genetic Variation
Investigations
Linkage Disequilibrium - genetics
Studies
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Summary:The cosmopolitan inversion In(3R)Payne in Drosophila melanogaster decreases in frequency with increasing distance from the equator on three continents, indicating it is subject to strong natural selection. We investigated patterns of genetic variation and linkage disequilibrium (LD) in 24 molecular markers located within and near In(3R)Payne to determine if different parts of the inversion responded to selection the same way. We found reduced variation in the markers we used compared to others distributed throughout the genome, consistent with the inversion having a relatively recent origin (
ISSN:0016-6731
1943-2631
1943-2631
DOI:10.1534/genetics.105.053173