Effects of feeding bacterial lipopolysaccharide and dextran sulphate on the development of oral tolerance to contact sensitizing agents

The effect of feeding the B-cell mitogens Escherichia coli lipopolysaccharide and dextran sulphate on the development of orally induced tolerance to the contact sensitizing agent picryl chloride was studied in mice. Feeding either agent throughout the experiment or during tolerization, increased the...

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Bibliographic Details
Published in:Immunology 1980-11, Vol.41 (3), p.617-621
Main Authors: Newby, T.J, Stokes, C.R, Bourne, F.J
Format: Article
Language:English
Subjects:
Animals
antigens
Antigens - administration & dosage
Dextrans - immunology
Diet
Hypersensitivity, Delayed - immunology
Immune Tolerance
Lipopolysaccharides - immunology
Male
Mice
Mice, Inbred CBA
Picryl Chloride - immunology
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Summary:The effect of feeding the B-cell mitogens Escherichia coli lipopolysaccharide and dextran sulphate on the development of orally induced tolerance to the contact sensitizing agent picryl chloride was studied in mice. Feeding either agent throughout the experiment or during tolerization, increased the tolerizing effect of a single feed of picryl chloride.
ISSN:0019-2805
1365-2567