analysis of polygenes affecting wing shape on chromosome 3 in Drosophila melanogaster

Loci on the third chromosome of Drosophila melanogaster that affect an index of wing shape were mapped, using recombinant isogenic lines, with transposable elements as markers. Many genes with small subequal effects are dispersed along the whole chromosome. Their alleles act nearly additively in het...

Full description

Saved in:
Bibliographic Details
Published in:Genetics (Austin) 1999-10, Vol.153 (2), p.773-786
Main Authors: Weber, K, Eisman, R, Morey, L, Patty, A, Sparks, J, Tausek, M, Zeng, Z.B
Format: Article
Language:English
Subjects:
additive effect
alleles
anatomy and morphology
Animals
autosomes
body regions
chromosome 3
Chromosome Mapping
Crosses, Genetic
Crossing Over, Genetic
Drosophila melanogaster
Drosophila melanogaster - anatomy & histology
Drosophila melanogaster - genetics
Female
gene location
genes
Genes, Insect
genetic effects
Genetic Markers
genetic models
genetic techniques and protocols
halteres
legs
loci
Male
multiple interval mapping
Phenotype
phenotypic variation
polygenic inheritance
Quantitative Trait, Heritable
quantitative traits
wings
Wings, Animal - anatomy & histology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Loci on the third chromosome of Drosophila melanogaster that affect an index of wing shape were mapped, using recombinant isogenic lines, with transposable elements as markers. Many genes with small subequal effects are dispersed along the whole chromosome. Their alleles act nearly additively in heterozygotes. They have small correlated effects on leg shape, but no detectable effects on halteres. Small negative net interactions occur over most of the chromosome. The data set of 519 recombinant isogenic lines can be explained reasonably well by two models. One model posits an indefinitely large number of loci with no interactions. The other model posits 11 loci with additive effects whose sum equals the total phenotypic range and with large positive and negative interactions that nearly cancel each other.
ISSN:0016-6731
1943-2631
1943-2631
DOI:10.1093/genetics/153.2.773