Coverage of oncology drug indication concepts and compositional semantics by SNOMED-CT

To evaluate SNOMED-CT 's ability to represent simple and compositional concepts in FDA approved oncology drug indications. Oncology drug indications were decomposed into single and compositional concepts. SNOMED-CT's coverage of single concepts and the semantics needed to create compositio...

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Bibliographic Details
Published in:AMIA ... Annual Symposium proceedings 2003, Vol.2003, p.115-119
Main Authors: Brown, Steven H, Bauer, Brent A, Wahner-Roedler, Dietland L, Elkin, Peter L
Format: Article
Language:English
Subjects:
Antineoplastic Agents - classification
Humans
Medical Oncology - classification
Neoplasms - drug therapy
Semantics
Systematized Nomenclature of Medicine
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Summary:To evaluate SNOMED-CT 's ability to represent simple and compositional concepts in FDA approved oncology drug indications. Oncology drug indications were decomposed into single and compositional concepts. SNOMED-CT's coverage of single concepts and the semantics needed to create compositional concepts were evaluated using automated and manual techniques. SNOMED-CT covered 86.3% of single concepts present in oncology drug indications; 11.3% of indications were covered completely. Coverage was best for concepts describing diseases, anatomy, and patient characteristics. Medications accounted for 50.5% of missing concepts. Excluding drug names, 45.2% of indications were completely represented. SNOMED-CT's semantics completely represented 60.1% of compositional expressions. SNOMED-CT's overall coverage of the concepts in oncology drug indications was good. Improvements or alternatives are needed for medications and semantics.
ISSN:1559-4076