PHARMACOLOGICAL ACTIVITY OF AN AQUEOUS EXTRACT OF THE LEAVES OF THE MALAYAN RENGAS TREE GLUTA RENGHAS

A pharmacological analysis of an aqueous extract of the leaves of Gluta renghas has been carried out. It has been shown that the extract contained a heat‐stable, anticholinesterase agent. A heart‐stimulating substance was also shown to be present in the extract. Intravenous injection of the extract...

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Bibliographic Details
Published in:British Journal of Pharmacology and Chemotherapy 1960-09, Vol.15 (3), p.440-447
Main Authors: LIN, R. C. Y., WHITTOW, G. C.
Format: Article
Language:English
Subjects:
Anacardiaceae
Animals
Cats
Cholinesterase Inhibitors
Injections, Intravenous
Old Medline
Plant Extracts
Plant Leaves
Respiration
Serotonin
Trees
Water
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Summary:A pharmacological analysis of an aqueous extract of the leaves of Gluta renghas has been carried out. It has been shown that the extract contained a heat‐stable, anticholinesterase agent. A heart‐stimulating substance was also shown to be present in the extract. Intravenous injection of the extract into the anaesthetized cat produced changes of arterial blood pressure, venous pressure and respiration which were reduced or abolished by vagotomy. The leaves contained approximately 0.1 μg./g. of 5‐hydroxytryptamine‐like activity.
ISSN:0366-0826
1476-5381
DOI:10.1111/j.1476-5381.1960.tb01270.x