Comparative sequence analysis of tmRNA

Minimal secondary structures of the bacterial and plastid tmRNAs were derived by comparative analyses of 50 aligned tmRNA sequences. The structures include 12 helices and four pseudoknots and are refinements of earlier versions, but include only those base pairs for which there is comparative eviden...

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Bibliographic Details
Published in:Nucleic acids research 1999-05, Vol.27 (10), p.2063-2071
Main Authors: Zwieb, Christian, Wower, Iwona, Wower, Jacek
Format: Article
Language:English
Subjects:
Bacteria - chemistry
Bacteria - genetics
Base Sequence
Models, Molecular
Molecular Sequence Data
Nucleic Acid Conformation
RNA, Bacterial - chemistry
RNA, Bacterial - genetics
RNA, Messenger - chemistry
RNA, Messenger - genetics
RNA, Transfer - chemistry
RNA, Transfer - genetics
Sequence Analysis, RNA
Sequence Homology, Nucleic Acid
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Summary:Minimal secondary structures of the bacterial and plastid tmRNAs were derived by comparative analyses of 50 aligned tmRNA sequences. The structures include 12 helices and four pseudoknots and are refinements of earlier versions, but include only those base pairs for which there is comparative evidence. Described are the conserved and variable features of the tmRNAs from a wide phylogenetic spectrum, the structural properties specific to the bacterial subgroups and preliminary 3-dimensional models from the pseudoknotted regions.
ISSN:0305-1048
1362-4962
DOI:10.1093/nar/27.10.2063