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Adherence to Combination Antiretroviral Therapies in HIV Patients of Low Health Literacy
OBJECTIVE: To test the significance of health literacy relative to other predictors of adherence to treatment for HIV and AIDS. PARTICIPANTS: Community sample of HIV‐seropositive men (n = 138) and women (n = 44) currently taking a triple‐drug combination of antiretroviral therapies for HIV infection...
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| Published in: | Journal of general internal medicine : JGIM 1999-05, Vol.14 (5), p.267-273 |
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| container_end_page | 273 |
| container_issue | 5 |
| container_start_page | 267 |
| container_title | Journal of general internal medicine : JGIM |
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| creator | Kalichman, Seth C. Ramachandran, Bineetha Catz, Sheryl |
| description | OBJECTIVE: To test the significance of health literacy relative to other predictors of adherence to treatment for HIV and AIDS.
PARTICIPANTS: Community sample of HIV‐seropositive men (n = 138) and women (n = 44) currently taking a triple‐drug combination of antiretroviral therapies for HIV infection; 60% were ethnic minorities, and 73% had been diagnosed with AIDS.
MEASUREMENTS: An adapted form of the Test of Health Literacy in Adults (TOFHLA), a comprehensive health and treatment interview that included 2‐day recall of treatment adherence and reasons for nonadherence, and measures of substance abuse, social support, emotional distress, and attitudes toward primary care providers.
MAIN RESULTS: Multiple logistic regression showed that education and health literacy were significant and independent predictors of 2‐day treatment adherence after controlling for age, ethnicity, income, HIV symptoms, substance abuse, social support, emotional distress, and attitudes toward primary care providers. Persons of low literacy were more likely to miss treatment doses because of confusion, depression, and desire to cleanse their body than were participants with higher health literacy.
CONCLUSIONS: Interventions are needed to help persons of low literacy adhere to antiretroviral therapies. |
| doi_str_mv | 10.1046/j.1525-1497.1999.00334.x |
| format | article |
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PARTICIPANTS: Community sample of HIV‐seropositive men (n = 138) and women (n = 44) currently taking a triple‐drug combination of antiretroviral therapies for HIV infection; 60% were ethnic minorities, and 73% had been diagnosed with AIDS.
MEASUREMENTS: An adapted form of the Test of Health Literacy in Adults (TOFHLA), a comprehensive health and treatment interview that included 2‐day recall of treatment adherence and reasons for nonadherence, and measures of substance abuse, social support, emotional distress, and attitudes toward primary care providers.
MAIN RESULTS: Multiple logistic regression showed that education and health literacy were significant and independent predictors of 2‐day treatment adherence after controlling for age, ethnicity, income, HIV symptoms, substance abuse, social support, emotional distress, and attitudes toward primary care providers. Persons of low literacy were more likely to miss treatment doses because of confusion, depression, and desire to cleanse their body than were participants with higher health literacy.
CONCLUSIONS: Interventions are needed to help persons of low literacy adhere to antiretroviral therapies.</description><identifier>ISSN: 0884-8734</identifier><identifier>EISSN: 1525-1497</identifier><identifier>DOI: 10.1046/j.1525-1497.1999.00334.x</identifier><identifier>PMID: 10337035</identifier><language>eng</language><publisher>Boston, MA, USA: Blackwell Science Inc</publisher><subject>Acquired immune deficiency syndrome ; Acquired Immunodeficiency Syndrome - drug therapy ; Adult ; Age Factors ; AIDS ; AIDS treatment ; AIDS/HIV ; Anti-HIV Agents - administration & dosage ; Antiretroviral drugs ; Biological and medical sciences ; Confidence Intervals ; Data Collection ; Drug abuse ; Drug dosages ; Drug therapy ; Drug Therapy, Combination ; Educational Status ; Female ; Health education ; Health literacy ; HIV ; HIV infection ; HIV Infections - drug therapy ; Human immunodeficiency virus ; Human viral diseases ; Humans ; Infections ; Infectious diseases ; Internal medicine ; Logistic Models ; Male ; Medical sciences ; medication adherence ; Mental depression ; Miscellaneous ; Odds Ratio ; Original ; Patient compliance ; Patient Compliance - statistics & numerical data ; Patient Education as Topic ; Prevention and actions ; Primary care ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Reading comprehension ; Sampling Studies ; Sex Factors ; Social support ; Socioeconomic Factors ; United States ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids</subject><ispartof>Journal of general internal medicine : JGIM, 1999-05, Vol.14 (5), p.267-273</ispartof><rights>1999 by the Society of General Internal Medicine</rights><rights>1999 INIST-CNRS</rights><rights>Society of General Internal Medicine 1999</rights><rights>1999 by the Society of General Internal Medicine 1999</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5914-1677d65f50851e4cf0a729abad402ac419ceff7d9007b41f3417bd3c77194cdc3</citedby><cites>FETCH-LOGICAL-c5914-1677d65f50851e4cf0a729abad402ac419ceff7d9007b41f3417bd3c77194cdc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1496573/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1496573/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1781222$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10337035$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kalichman, Seth C.</creatorcontrib><creatorcontrib>Ramachandran, Bineetha</creatorcontrib><creatorcontrib>Catz, Sheryl</creatorcontrib><title>Adherence to Combination Antiretroviral Therapies in HIV Patients of Low Health Literacy</title><title>Journal of general internal medicine : JGIM</title><addtitle>J Gen Intern Med</addtitle><description>OBJECTIVE: To test the significance of health literacy relative to other predictors of adherence to treatment for HIV and AIDS.
PARTICIPANTS: Community sample of HIV‐seropositive men (n = 138) and women (n = 44) currently taking a triple‐drug combination of antiretroviral therapies for HIV infection; 60% were ethnic minorities, and 73% had been diagnosed with AIDS.
MEASUREMENTS: An adapted form of the Test of Health Literacy in Adults (TOFHLA), a comprehensive health and treatment interview that included 2‐day recall of treatment adherence and reasons for nonadherence, and measures of substance abuse, social support, emotional distress, and attitudes toward primary care providers.
MAIN RESULTS: Multiple logistic regression showed that education and health literacy were significant and independent predictors of 2‐day treatment adherence after controlling for age, ethnicity, income, HIV symptoms, substance abuse, social support, emotional distress, and attitudes toward primary care providers. Persons of low literacy were more likely to miss treatment doses because of confusion, depression, and desire to cleanse their body than were participants with higher health literacy.
CONCLUSIONS: Interventions are needed to help persons of low literacy adhere to antiretroviral therapies.</description><subject>Acquired immune deficiency syndrome</subject><subject>Acquired Immunodeficiency Syndrome - drug therapy</subject><subject>Adult</subject><subject>Age Factors</subject><subject>AIDS</subject><subject>AIDS treatment</subject><subject>AIDS/HIV</subject><subject>Anti-HIV Agents - administration & dosage</subject><subject>Antiretroviral drugs</subject><subject>Biological and medical sciences</subject><subject>Confidence Intervals</subject><subject>Data Collection</subject><subject>Drug abuse</subject><subject>Drug dosages</subject><subject>Drug therapy</subject><subject>Drug Therapy, Combination</subject><subject>Educational Status</subject><subject>Female</subject><subject>Health education</subject><subject>Health literacy</subject><subject>HIV</subject><subject>HIV infection</subject><subject>HIV Infections - drug therapy</subject><subject>Human immunodeficiency virus</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Internal medicine</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medical sciences</subject><subject>medication adherence</subject><subject>Mental depression</subject><subject>Miscellaneous</subject><subject>Odds Ratio</subject><subject>Original</subject><subject>Patient compliance</subject><subject>Patient Compliance - statistics & numerical data</subject><subject>Patient Education as Topic</subject><subject>Prevention and actions</subject><subject>Primary care</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Reading comprehension</subject><subject>Sampling Studies</subject><subject>Sex Factors</subject><subject>Social support</subject><subject>Socioeconomic Factors</subject><subject>United States</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. 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Aids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kalichman, Seth C.</creatorcontrib><creatorcontrib>Ramachandran, Bineetha</creatorcontrib><creatorcontrib>Catz, Sheryl</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>PML(ProQuest Medical Library)</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of general internal medicine : JGIM</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kalichman, Seth C.</au><au>Ramachandran, Bineetha</au><au>Catz, Sheryl</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adherence to Combination Antiretroviral Therapies in HIV Patients of Low Health Literacy</atitle><jtitle>Journal of general internal medicine : JGIM</jtitle><addtitle>J Gen Intern Med</addtitle><date>1999-05</date><risdate>1999</risdate><volume>14</volume><issue>5</issue><spage>267</spage><epage>273</epage><pages>267-273</pages><issn>0884-8734</issn><eissn>1525-1497</eissn><abstract>OBJECTIVE: To test the significance of health literacy relative to other predictors of adherence to treatment for HIV and AIDS.
PARTICIPANTS: Community sample of HIV‐seropositive men (n = 138) and women (n = 44) currently taking a triple‐drug combination of antiretroviral therapies for HIV infection; 60% were ethnic minorities, and 73% had been diagnosed with AIDS.
MEASUREMENTS: An adapted form of the Test of Health Literacy in Adults (TOFHLA), a comprehensive health and treatment interview that included 2‐day recall of treatment adherence and reasons for nonadherence, and measures of substance abuse, social support, emotional distress, and attitudes toward primary care providers.
MAIN RESULTS: Multiple logistic regression showed that education and health literacy were significant and independent predictors of 2‐day treatment adherence after controlling for age, ethnicity, income, HIV symptoms, substance abuse, social support, emotional distress, and attitudes toward primary care providers. Persons of low literacy were more likely to miss treatment doses because of confusion, depression, and desire to cleanse their body than were participants with higher health literacy.
CONCLUSIONS: Interventions are needed to help persons of low literacy adhere to antiretroviral therapies.</abstract><cop>Boston, MA, USA</cop><pub>Blackwell Science Inc</pub><pmid>10337035</pmid><doi>10.1046/j.1525-1497.1999.00334.x</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0884-8734 |
| ispartof | Journal of general internal medicine : JGIM, 1999-05, Vol.14 (5), p.267-273 |
| issn | 0884-8734 1525-1497 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1496573 |
| source | Open Access: PubMed Central; Springer Nature |
| subjects | Acquired immune deficiency syndrome Acquired Immunodeficiency Syndrome - drug therapy Adult Age Factors AIDS AIDS treatment AIDS/HIV Anti-HIV Agents - administration & dosage Antiretroviral drugs Biological and medical sciences Confidence Intervals Data Collection Drug abuse Drug dosages Drug therapy Drug Therapy, Combination Educational Status Female Health education Health literacy HIV HIV infection HIV Infections - drug therapy Human immunodeficiency virus Human viral diseases Humans Infections Infectious diseases Internal medicine Logistic Models Male Medical sciences medication adherence Mental depression Miscellaneous Odds Ratio Original Patient compliance Patient Compliance - statistics & numerical data Patient Education as Topic Prevention and actions Primary care Public health. Hygiene Public health. Hygiene-occupational medicine Reading comprehension Sampling Studies Sex Factors Social support Socioeconomic Factors United States Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids |
| title | Adherence to Combination Antiretroviral Therapies in HIV Patients of Low Health Literacy |
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