Altered immunity and diabetes in the BB rat

In recent years, considerable information has been gathered regarding cellular and humoral immunity in the BB rats. This report summarizes the available information, highlights controversies, and states hypotheses regarding the aetiology. Comparisons and contrasts with human type 1 diabetes are draw...

Full description

Saved in:
Bibliographic Details
Published in:Clinical and experimental immunology 1984-07, Vol.57 (1), p.1-11
Main Authors: YALE, Y.-F, MARLISS, E. B
Format: Article
Language:English
Subjects:
Animals
Antibody Formation
Biological and medical sciences
Diabetes Mellitus, Type 1 - etiology
Diabetes Mellitus, Type 1 - immunology
Diabetes. Impaired glucose tolerance
Disease Models, Animal - immunology
Disease Susceptibility
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Female
Immunosuppression
Islets of Langerhans - immunology
Leukocyte Count
Lymphocytes - classification
Male
Medical sciences
Pancreatitis - immunology
Rats
Rats, Inbred Strains
T-Lymphocytes - immunology
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In recent years, considerable information has been gathered regarding cellular and humoral immunity in the BB rats. This report summarizes the available information, highlights controversies, and states hypotheses regarding the aetiology. Comparisons and contrasts with human type 1 diabetes are drawn. The findings are presented in the context of the pathogenetic scheme proposed by Cahill & McDevitt (1981).
ISSN:0009-9104
1365-2249