Dexamethasone enhancement of the induction of cells bearing receptors for IgM in human peripheral blood lymphocyte culture

Using a low density culture technique which allows normal human peripheral blood T cells to proliferate actively in vitro when stimulated by mitogens, it is shown that dexamethasone enhances the spontaneous induction of cells bearing receptors for the Fc of IgM. Dexamethasone has no effect on the in...

Full description

Saved in:
Bibliographic Details
Published in:Clinical and experimental immunology 1980-04, Vol.40 (1), p.178-185
Main Authors: Tillyer, C R, Butterworth, P H
Format: Article
Language:English
Subjects:
Cells, Cultured
Dexamethasone - pharmacology
Humans
Immunoglobulin M - metabolism
Lymphocytes - drug effects
Lymphocytes - immunology
Mitosis - drug effects
Receptors, Fc - biosynthesis
Receptors, Fc - drug effects
Rosette Formation
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Using a low density culture technique which allows normal human peripheral blood T cells to proliferate actively in vitro when stimulated by mitogens, it is shown that dexamethasone enhances the spontaneous induction of cells bearing receptors for the Fc of IgM. Dexamethasone has no effect on the induction of cells bearing receptors for the Fc of IgG.
ISSN:0009-9104
1365-2249