Organ mercury levels in infants with omphaloceles treated with organic mercurial antiseptic

Samples of fresh and fixed tissues from infants with exomphalos treated by thiomersal application were analysed for mercury content. The results showed that thiomersal can induce blood and organ levels of organic mercury which are well in excess of the minimum toxic level in adults and fetuses. The...

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Bibliographic Details
Published in:Archives of disease in childhood 1977-12, Vol.52 (12), p.962-964
Main Authors: Fagan, D G, Pritchard, J S, Clarkson, T W, Greenwood, M R
Format: Article
Language:English
Subjects:
Brain - metabolism
Ethylmercury Compounds - poisoning
Hernia, Umbilical - drug therapy
Hernia, Umbilical - metabolism
Humans
Infant
Infants
Kidney - metabolism
Liver - metabolism
Mercury
Mercury - metabolism
Thimerosal - poisoning
Thimerosal - therapeutic use
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Summary:Samples of fresh and fixed tissues from infants with exomphalos treated by thiomersal application were analysed for mercury content. The results showed that thiomersal can induce blood and organ levels of organic mercury which are well in excess of the minimum toxic level in adults and fetuses. The analysis of fresh and fixed tissues must be carefully controlled against normal tissues in order to interpret mercury levels accurately.
ISSN:0003-9888
1468-2044
DOI:10.1136/adc.52.12.962