Parathyroid hormone and 25-hydroxyvitamin D concentrations in sick and normal elderly people

Serum 25-hydroxyvitamin D and immunoreactive parathyroid hormone concentrations were measured in normal elderly subjects living at home and in sick elderly patients in hospital. Normal old people tended to have high 25-hydroxyvitamin D and low parathyroid hormone concentrations; in the sick elderly...

Full description

Saved in:
Bibliographic Details
Published in:BMJ 1983-08, Vol.287 (6391), p.521-523
Main Authors: Petersen, M M, Briggs, R S, Ashby, M A, Reid, R I, Hall, M R, Wood, P J, Clayton, B E
Format: Article
Language:English
Subjects:
25-Hydroxyvitamin D 2
Aged
Alkaline Phosphatase - blood
Biochemistry
Biological and medical sciences
Calcium
Endocrinopathies
Ergocalciferols - analogs & derivatives
Ergocalciferols - blood
Female
Geriatrics
Hormones
Humans
Hyperparathyroidism - diagnosis
Kidney Diseases - blood
Male
Malignant tumors
Medical sciences
Middle Aged
Older adults
Parathyroid Hormone - blood
Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases)
Phosphatases
Primary hyperparathyroidism
Renal function
Serum albumins
Vitamin D
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Serum 25-hydroxyvitamin D and immunoreactive parathyroid hormone concentrations were measured in normal elderly subjects living at home and in sick elderly patients in hospital. Normal old people tended to have high 25-hydroxyvitamin D and low parathyroid hormone concentrations; in the sick elderly this pattern was reversed. The raised serum parathyroid hormone concentrations in the sick elderly were not due to poor renal function and may have been a response to vitamin D deficiency. A high serum parathyroid hormone concentration in an elderly patient must be interpreted in the light of the patient's general health and nutritional state. Caution is needed in diagnosing primary hyperparathyroidism in this age group.
ISSN:0007-1447
0267-0623
0959-8138
1468-5833
DOI:10.1136/bmj.287.6391.521