GeneHopper: a web-based search engine to link gene-expression platforms through GenBank accession numbers

Global gene-expression analysis is carried out using different technologies that are either array- or sequence-tag-based. To compare experiments that are performed on these different platforms, array probes and sequence tags need to be linked. An additional challenge is cross-referencing between spe...

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Bibliographic Details
Published in:Genome biology 2003-01, Vol.4 (5), p.R35-545, Article R35
Main Authors: Svensson, B Anders T, Kreeft, Arja J, van Ommen, Gert-Jan B, den Dunnen, Johan T, Boer, Judith M
Format: Article
Language:English
Subjects:
animal models
Animals
Computational Biology - methods
Computational Biology - statistics & numerical data
Databases, Nucleic Acid - statistics & numerical data
gene expression
Gene Expression Profiling - statistics & numerical data
Humans
Internet
Mice
National Center for Biotechnology Information
Rats
Software
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Summary:Global gene-expression analysis is carried out using different technologies that are either array- or sequence-tag-based. To compare experiments that are performed on these different platforms, array probes and sequence tags need to be linked. An additional challenge is cross-referencing between species, to compare human profiles with those obtained in a mouse model, for example. We have developed the web-based search engine GeneHopper to link different expression resources based on UniGene clusters and HomoloGene orthologs databases of the National Center for Biotechnology Information (NCBI).
ISSN:1474-760X
1465-6906
1474-760X
1465-6914
DOI:10.1186/gb-2003-4-5-r35