Efficacy of orbifloxacin tablets for the treatment of superficial and deep pyoderma due to Staphylococcus intermedius infection in dogs

Orbifloxacin tablets were administered orally to 23 dogs with superficial and/or deep staphylococcal pyoderma. Response to therapy was excellent in 95.6% of the dogs. Duration of therapy varied from 21 to 40 days (average 29 days) for dogs having only superficial infections, and from 25 to 150 days...

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Bibliographic Details
Published in:Canadian veterinary journal 2006-10, Vol.47 (10), p.999-1002
Main Authors: Scott, D.W, Peters, J, Miller, W.H. Jr
Format: Article
Language:English
Subjects:
adverse effects
Animals
Anti-Bacterial Agents - adverse effects
Anti-Bacterial Agents - therapeutic use
antimicrobial agents
bacterial infections
Ciprofloxacin - adverse effects
Ciprofloxacin - analogs & derivatives
Ciprofloxacin - therapeutic use
disease severity
dog diseases
Dog Diseases - drug therapy
Dogs
drug evaluation
drug therapy
Female
Male
oral administration
orbifloxacin
pyoderma
Pyoderma - drug therapy
Pyoderma - veterinary
relapse
Scientific
Staphylococcal Infections - drug therapy
Staphylococcal Infections - veterinary
Staphylococcus intermedius
Time Factors
Treatment Outcome
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Summary:Orbifloxacin tablets were administered orally to 23 dogs with superficial and/or deep staphylococcal pyoderma. Response to therapy was excellent in 95.6% of the dogs. Duration of therapy varied from 21 to 40 days (average 29 days) for dogs having only superficial infections, and from 25 to 150 days (average 72 days) for dogs having deep infections. Relapses occurred in 18% of the dogs within a 3-month period. One dog developed a presumed adverse cutaneous drug reaction. Under the conditions of this study, orbifloxacin was an effective, safe, and convenient antibiotic for the treatment of superficial and deep staphylococcal pyoderma in dogs.
ISSN:0008-5286