Pancreatic Exocrine Function in Maturity Onset Diabetes Mellitus

Exocrine pancreatic function was studied in 14 inpatients with newly diagnosed maturity onset diabetes mellitus. Five patients had clinical and biochemical evidence of pancreatic disease (two carcinoma, three pancreatitis). The other nine patients had no clinical pancreatic disease but all except on...

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Bibliographic Details
Published in:BMJ 1973-10, Vol.4 (5883), p.25-27
Main Authors: Baron, J. H., Nabarro, J. D. N.
Format: Article
Language:English
Subjects:
Adult
Aged
Amylases - blood
Bicarbonates
Bicarbonates - analysis
Blood
Blood Glucose - analysis
Carcinoma
Diabetes Complications
Diabetes mellitus
Diabetes Mellitus - physiopathology
Endocrine system diseases
Fatty Acids - analysis
Feces - analysis
Female
Food
Gastroenterology
Glucose Tolerance Test
Humans
Inhalation
Male
Middle Aged
Pancreas - physiopathology
Pancreatic diseases
Pancreatic function tests
Pancreatic Neoplasms - complications
Pancreatitis
Pancreatitis - complications
Papers and Originals
Secretin - analysis
Starch - metabolism
Starches
Trypsin - analysis
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Summary:Exocrine pancreatic function was studied in 14 inpatients with newly diagnosed maturity onset diabetes mellitus. Five patients had clinical and biochemical evidence of pancreatic disease (two carcinoma, three pancreatitis). The other nine patients had no clinical pancreatic disease but all except one had at least one abnormal result of pancreatic function tests. None of this group with idiopathic diabetes mellitus developed any clinical evidence of exocrine pancreatic disease over the next five years. Mild abnormalities of exocrine pancreatic function in newly diagnosed patients with diabetes but without clinical evidence of pancreatic disease do not usually develop into overt pancreatic disease, and are therefore probably clinically unimportant.
ISSN:0007-1447
0959-8138
1468-5833
DOI:10.1136/bmj.4.5883.25