Pregnanediols and breast milk jaundice

Samples of breast milk collected from mothers of infants with breast milk jaundice were analysed for 5 beta-pregnane-3 alpha, 20 beta-diol, and other pregnanediols using gas chromatography-high resolution mass spectrometry. None was detected in any of the specimens and therefore it is unlikely to be...

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Bibliographic Details
Published in:Archives of disease in childhood 1981-06, Vol.56 (6), p.474-476
Main Authors: Murphy, J F, Hughes, I, Verrier Jones, E R, Gaskell, S, Pike, A W
Format: Article
Language:English
Subjects:
Breast Feeding
Breast milk
Female
Gas chromatography
Humans
Infant, Newborn
Infants
Jaundice, Neonatal - etiology
Mass spectrometry
Milk, Human - analysis
Pregnanediol - analysis
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Summary:Samples of breast milk collected from mothers of infants with breast milk jaundice were analysed for 5 beta-pregnane-3 alpha, 20 beta-diol, and other pregnanediols using gas chromatography-high resolution mass spectrometry. None was detected in any of the specimens and therefore it is unlikely to be the inhibitory factor in bilirubin conjugation. The plasma osmolalities of the infants, which were determined at the onset of jaundice, were within normal limits.
ISSN:0003-9888
1468-2044
DOI:10.1136/adc.56.6.474